857040-81-4Relevant articles and documents
Novel pseudopeptides incorporating a benzodiazepine-based turn mimetic - Targeting Mycobacterium tuberculosis ribonucleotide reductase
Nurbo, Johanna,Ericsson, Daniel J.,Rosenstr?m, Ulrika,Muthas, Daniel,Jansson, Anna M.,Lindeberg, Gunnar,Unge, Torsten,Karlén, Anders
, p. 1992 - 2000 (2013/05/08)
Peptides mimicking the C-terminus of the small subunit (R2) of Mycobacterium tuberculosis ribonucleotide reductase (RNR) can compete for binding to the large subunit (R1) and thus inhibit RNR activity. Moreover, it has been suggested that the binding of t