861659-75-8

Basic information

• Product Name: 3-phenylhexanoic acid methyl ester
• CAS NO: 861659-75-8
• Molecular Weight: 206.285
• Mol File: 861659-75-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-phenylhexanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylhexanoic acid methyl ester(861659-75-8)
• EPA Substance Registry System: 3-phenylhexanoic acid methyl ester(861659-75-8)

Safety Data

• Hazardous Substances Data: 861659-75-8(Hazardous Substances Data)

Upstream product

• 13894-63-8 methyl (E)-hex-2-enoate 
• 2996-92-1 phenyl trimethylsiloxane 
• 98-80-6 phenylboronic acid 
• 591-51-5 phenyllithium 
• 186581-53-3 diazomethane 
• 71845-01-7 (3S)-3-phenylheptanoic acid 

Downstream Products

• 103042-35-9 rac.-Di-(o-anisyl)-3-phenyl-hexanol-⁽¹⁾ 

Relevant articles and documents

Asymmetric 1,4-addition of aryltrialkoxysilanes to α,β-unsaturated esters and amides catalyzed by a chiral rhodium complex

A highly enantioselective 1,4-addition of aryltrialkoxysilanes to α,β-unsaturated esters and amides was successfully catalyzed by a chiral rhodium complex generated from [Rh(cod)(MeCN)2]BF4 and (S)-BINAP.

Rhodium-catalyzed asymmetric 1,4-addition of arylboron reagents to α,β-unsaturated esters

Reaction of arylboron reagents, arylboronic acids or arylborates, which are readily accessible by lithiation of aryl bromides followed by treatment with trimethoxyborane, with α,β-unsaturated esters in the presence of rhodium/(S)-binap catalyst proceeded with high enantioselectivity to give high yields of optically active β-aryl esters of up to 98% ee. The enantioselectivity depends on the steric bulkiness of the ester moiety.