863307-01-1

Basic information

• Product Name: [4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-(4-methylpiperazin-1-yl)methanone
• Synonyms: [4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-(4-methylpiperazin-1-yl)methanone
• CAS NO: 863307-01-1
• Molecular Weight: 355.827
• Mol File: 863307-01-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-(4-methylpiperazin-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-(4-methylpiperazin-1-yl)methanone(863307-01-1)
• EPA Substance Registry System: [4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-(4-methylpiperazin-1-yl)methanone(863307-01-1)

Safety Data

• Hazardous Substances Data: 863307-01-1(Hazardous Substances Data)

Upstream product

• 109-01-3 1-methyl-piperazine 
• 863307-00-0 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoic acid 
• 1011716-97-4 methyl 4-(4-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoate 
• 1011717-00-2 methyl 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoate 
• 1011716-95-2 ethyl 2-amino-5-(4-(methoxycarbonyl)phenyl)-1H-pyrrole-3-carboxylate 
• 56893-25-5 methyl 4-(2-bromoacetyl)benzoate 
• 187724-93-2 4-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-6-yl)benzoic acid ethyl ester 

Relevant articles and documents

Design of Potent and Selective Covalent Inhibitors of Bruton's Tyrosine Kinase Targeting an Inactive Conformation

Bruton's tyrosine kinase (BTK) is a member of the TEC kinase family and is selectively expressed in a subset of immune cells. It is a key regulator of antigen receptor signaling in B cells and of Fc receptor signaling in mast cells and macrophages. A BTK

7H-PYRROLOPYRIMIDINE DERIVATIVES

The invention relates to 7H-pyrrolo[2,3-d]pyrimidine derivatives of formula (I), wherein the symbols and substituents are as defined in the description, to processes for the preparation thereof, to pharmaceutical compositions comprising such derivatives a