863599-38-6

Basic information

• Product Name: 2-chloro-7-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine
• Synonyms: 2-chloro-7-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine
• CAS NO: 863599-38-6
• Molecular Weight: 230.656
• Mol File: 863599-38-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-chloro-7-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-7-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine(863599-38-6)
• EPA Substance Registry System: 2-chloro-7-pyridin-2-yl-7H-pyrrolo[2,3-d]pyrimidine(863599-38-6)

Safety Data

• Hazardous Substances Data: 863599-38-6(Hazardous Substances Data)

Upstream product

• 109-04-6 2-bromo-pyridine 
• 335654-06-3 2-chloro-7H-pyrrolo[2,3-d]pyrimidine 

Downstream Products

• 863599-15-9 (7-pyridin-2-yl-7H-pyrrolol[2,3-d]pyrimidin-2-yl)-(3,4,5,-trimethoxy-phenyl)-amine 

Relevant articles and documents

Novel Mps1 kinase inhibitors: From purine to pyrrolopyrimidine and quinazoline leads

Mps1, also known as TTK, is a mitotic checkpoint protein kinase that has become a promising new target of cancer research. In an effort to improve the lead-likeness of our recent Mps1 purine lead compounds, a scaffold hopping exercise has been undertaken.

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di