86409-29-2

Basic information

• Product Name: 4-Oxazolidinepropanoic acid, 2,5-dioxo-, 1,1-dimethylethyl ester, (4S)-
• CAS NO: 86409-29-2
• Molecular Formula: C10H15NO5
• Molecular Weight: 229.233
• Mol File: 86409-29-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Oxazolidinepropanoic acid, 2,5-dioxo-, 1,1-dimethylethyl ester, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxazolidinepropanoic acid, 2,5-dioxo-, 1,1-dimethylethyl ester, (4S)-(86409-29-2)
• EPA Substance Registry System: 4-Oxazolidinepropanoic acid, 2,5-dioxo-, 1,1-dimethylethyl ester, (4S)-(86409-29-2)

Safety Data

• Hazardous Substances Data: 86409-29-2(Hazardous Substances Data)

Upstream product

• 75-44-5 phosgene 
• 2419-56-9 L-glutamic acid 5-tert-butyl ester 
• 503-38-8 trichloromethyl chloroformate 

Downstream Products

• 129288-39-7 (S)-4-(2-tert-Butoxycarbonyl-ethyl)-2,5-dioxo-oxazolidine-3-carboxylic acid 9H-fluoren-9-ylmethyl ester 

Relevant articles and documents

POLYPEPT(O)ID-BASED GRAFT COPOLYMERS FOR IN VIVO IMAGING BY TETRAZINE TRANSCYCLOOCTENE CLICK CHEMISTRY

There is provided novel polypeptide-based carrier systems, which make it possible to label polymeric nanoparticles in the living organism. This enables new approaches in tumor diagnostics (high signal to background ratio) and radiotherapy (radiotherapy of solid tumors). The polypeptide-based carrier system comprises a polypept(o)idic comb (graft) copolymer, and one or more tetrazine bioorthogonal functional groups each linked to a diagnostic agent.

CONFORMATION SWITCHABLE ANTIMICROBIAL PEPTIDES AND METHODS OF USING THE SAME

The disclosure provides a class of pH-sensitive, helix/random conformation switchable antimicrobial polypeptide (HRS-AMP) compositions as a single agent to selectively kill bacteria (e.g., H. pylori) under acidic condition in the stomach with diminished bacterial resistance compared to currently used antibiotics. Methods of treating bacterial infections in the stomach are also provided.