865087-12-3 Usage
Description
(3aR,4R,5R,6aS)-4-[3S-(t-butyldimethylsiloxy)-5-phenyl-1E-pentenyl]-5-hydroxy-hexahydro-2H-cyclopenta[b]furan-2-ol is a complex organic compound characterized by a cyclopentafuran backbone, featuring a hydroxyl group and a pentenyl side chain with a siloxy group. Its stereochemistry is intricate, with multiple chiral centers, and it is highly functionalized, suggesting a range of potential biological activities and synthetic applications due to its structural complexity.
Uses
Used in Pharmaceutical Industry:
(3aR,4R,5R,6aS)-4-[3S-(t-butyldimethylsiloxy)-5-phenyl-1E-pentenyl]-5-hydroxy-hexahydro-2H-cyclopenta[b]furan-2-ol is used as a pharmaceutical candidate for its potential biological activities, which may include therapeutic applications due to its complex structure and multiple functional groups.
Used in Chemical Synthesis:
In the field of chemical synthesis, (3aR,4R,5R,6aS)-4-[3S-(t-butyldimethylsiloxy)-5-phenyl-1E-pentenyl]-5-hydroxy-hexahydro-2H-cyclopenta[b]furan-2-ol serves as a key intermediate or building block for the creation of more complex molecules, taking advantage of its reactive sites and chiral centers.
Used in Material Science:
(3aR,4R,5R,6aS)-4-[3S-(t-butyldimethylsiloxy)-5-phenyl-1E-pentenyl]-5-hydroxy-hexahydro-2H-cyclopenta[b]furan-2-ol is utilized in material science for the development of novel materials with unique properties, such as polymers or composites, owing to its structural complexity and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 865087-12-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,5,0,8 and 7 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 865087-12:
(8*8)+(7*6)+(6*5)+(5*0)+(4*8)+(3*7)+(2*1)+(1*2)=193
193 % 10 = 3
So 865087-12-3 is a valid CAS Registry Number.
865087-12-3Relevant articles and documents
Synthesis of prostaglandin analogues, latanoprost and bimatoprost, using organocatalysis via a key bicyclic enal intermediate
Pr??vost, S??bastien,Thai, Karen,Sch??tzenmeister, Nina,Coulthard, Graeme,Erb, William,Aggarwal, Varinder K.
supporting information, p. 504 - 507 (2015/03/05)
Two antiglaucoma drugs, bimatoprost and latanoprost, which are analogues of the prostaglandin, PGF2?±, have been synthesized in just 7 and 8 steps, respectively. The syntheses employ an organocatalytic aldol reaction that converts succinaldehyde into a key bicyclic enal intermediate, which is primed for attachment of the required lower and upper side chains. By utilizing the crystalline lactone, the drug molecules were prepared in >99% ee.
