1393740-68-5 Usage
Description
(3aR,4R,5R,6aS)-4-[(3R)-(tert-butyldimethylsilyl)oxy-5-phenylpentyl]perhydrocyclopenta[b]furan-2,5-diol is a complex organic compound featuring a cyclopenta[b]furan structure. It is characterized by a perhydrocyclopenta[b]furan-2,5-diol core and a tert-butyldimethylsilyl-protected hydroxyl group attached to a phenylpentyl side chain. (3aR,4R,5R,6aS)-4-[(3R)-(tert-butyldimethylsilyl)oxy-5-phenylpentyl]perhydrocyclopenta[b]furan-2,5-diol is notable for its unique stereochemistry and functional groups, which may contribute to its biological activity and potential as a drug candidate.
Uses
Used in Organic Synthesis:
(3aR,4R,5R,6aS)-4-[(3R)-(tert-butyldimethylsilyl)oxy-5-phenylpentyl]perhydrocyclopenta[b]furan-2,5-diol is utilized as a building block in organic synthesis for the creation of more complex molecules. Its specific structure and functional groups make it a valuable component in the synthesis process.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3aR,4R,5R,6aS)-4-[(3R)-(tert-butyldimethylsilyl)oxy-5-phenylpentyl]perhydrocyclopenta[b]furan-2,5-diol is used as a compound of interest in drug discovery and development. Its unique stereochemistry and functional groups may offer biological activity, making it a potential candidate for further research and development as a pharmaceutical agent.
Check Digit Verification of cas no
The CAS Registry Mumber 1393740-68-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,3,7,4 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1393740-68:
(9*1)+(8*3)+(7*9)+(6*3)+(5*7)+(4*4)+(3*0)+(2*6)+(1*8)=185
185 % 10 = 5
So 1393740-68-5 is a valid CAS Registry Number.
1393740-68-5Relevant articles and documents
Synthesis of prostaglandin analogues, latanoprost and bimatoprost, using organocatalysis via a key bicyclic enal intermediate
Pr??vost, S??bastien,Thai, Karen,Sch??tzenmeister, Nina,Coulthard, Graeme,Erb, William,Aggarwal, Varinder K.
, p. 504 - 507 (2015/03/05)
Two antiglaucoma drugs, bimatoprost and latanoprost, which are analogues of the prostaglandin, PGF2?±, have been synthesized in just 7 and 8 steps, respectively. The syntheses employ an organocatalytic aldol reaction that converts succinaldehyde into a key bicyclic enal intermediate, which is primed for attachment of the required lower and upper side chains. By utilizing the crystalline lactone, the drug molecules were prepared in >99% ee.
