865540-40-5

Basic information

• Product Name: (R)-3-{(S)-3-Benzyloxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-propionyl}-4-isopropyl-oxazolidin-2-one
• Synonyms: (R)-3-{(S)-3-Benzyloxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-propionyl}-4-isopropyl-oxazolidin-2-one
• CAS NO: 865540-40-5
• Molecular Weight: 712.012
• Mol File: 865540-40-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-{(S)-3-Benzyloxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-propionyl}-4-isopropyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-{(S)-3-Benzyloxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-propionyl}-4-isopropyl-oxazolidin-2-one(865540-40-5)
• EPA Substance Registry System: (R)-3-{(S)-3-Benzyloxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-propionyl}-4-isopropyl-oxazolidin-2-one(865540-40-5)

Safety Data

• Hazardous Substances Data: 865540-40-5(Hazardous Substances Data)

Upstream product

• 865540-16-5 (R)-4-Isopropyl-3-{2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-acetyl}-oxazolidin-2-one 
• 17482-09-6 benzyl iodomethyl ether 
• 2749-70-4 bis(benzyloxy)methane 
• 105-13-5 4-Methoxybenzyl alcohol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 1118-59-8 3-methylbut-3-en-1-al 
• 865540-39-2 [(1R,2S)-2-(4-Methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-acetic acid 
• 865540-15-4 [(2R,3S)-2-Allyloxy-3-(4-methoxy-benzyloxy)-5-methyl-hex-5-enyloxy]-triisopropyl-silane 
• 865540-38-1 (2R,3S)-3-(4-Methoxy-benzyloxy)-5-methyl-1-triisopropylsilanyloxy-hex-5-en-2-ol 
• 865540-37-0 (2R,3S)-2-Allyloxy-5-methyl-1-triisopropylsilanyloxy-hex-5-en-3-ol 
• 865540-36-9 (2R,3S)-2-Allyloxy-5-methyl-hex-5-ene-1,3-diol 
• 865540-35-8 2,7-dimethylocta-1,7-diene-4,5-diol 

Downstream Products

• 865540-20-1 (2S,3R,5S,7S,8R)-2-Benzyloxymethyl-7-(4-methoxy-benzyloxy)-5-methyl-8-triisopropylsilanyloxymethyl-oxocan-3-ol 
• 865540-42-7 (2S,5R,7S,8R)-2-Benzyloxymethyl-7-(4-methoxy-benzyloxy)-5-methyl-8-triisopropylsilanyloxymethyl-oxocan-3-one 
• 865540-17-6 (R)-3-Benzyloxy-2-[(1R,2S)-2-(4-methoxy-benzyloxy)-4-methyl-1-triisopropylsilanyloxymethyl-pent-4-enyloxy]-propan-1-ol 

Relevant articles and documents

Enantioselective total synthesis of brevetoxin A: Unified strategy for the B, E, G, and J subunits

Brevetoxin A is a decacyclic ladder toxin that possesses 5-, 6-, 7-, 8-, and 9-membered oxacycles, as well as 22 tetrahedral stereocenters. Herein, we describe a unified approach to the B, E, G, and J rings based upon a ring-closing metathesis strategy from the corresponding dienes. The enolate technologies developed in our laboratory allowed access to the precursor acyclic dienes for the B, E, and G medium-ring ethers. The strategies developed for the syntheses of these four monocycles ultimately provided multigram quantities of each of the rings, supporting our efforts toward the completion of a convergent synthesis of brevetoxin A.