869294-78-0

Basic information

• Product Name: 2-Quinazolinecarboxylic acid, 1,4-dihydro-8-methoxy-4-oxo-, ethyl ester (9CI)
• Synonyms: 2-Quinazolinecarboxylic acid, 1,4-dihydro-8-methoxy-4-oxo-, ethyl ester (9CI)
• CAS NO: 869294-78-0
• Molecular Formula: C12H12N2O4
• Molecular Weight: 0
• Mol File: 869294-78-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Quinazolinecarboxylic acid, 1,4-dihydro-8-methoxy-4-oxo-, ethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Quinazolinecarboxylic acid, 1,4-dihydro-8-methoxy-4-oxo-, ethyl ester (9CI)(869294-78-0)
• EPA Substance Registry System: 2-Quinazolinecarboxylic acid, 1,4-dihydro-8-methoxy-4-oxo-, ethyl ester (9CI)(869294-78-0)

Safety Data

• Hazardous Substances Data: 869294-78-0(Hazardous Substances Data)

Upstream product

• 106782-78-9 3-methoxy-2-aminobenzamide 
• 3177-80-8 2-amino-3-methoxybenzoic acid 
• 869298-98-6 ethyl ((2-(aminocarbonyl)-6-methoxyphenyl)amino)(oxo)acetate 

Downstream Products

• 1360652-12-5 ethyl 4-chloro-8-methoxyquinazoline-2-carboxylate 

Relevant articles and documents

SUBSTITUTED 2- AMIDOQUINAZOL-4-ONES AS MATRIX METALLOPROTEINASE-13 INHIBITORS

The present invention provides a novel amide derivative having a matrix metalloproteinase inhibitory activity, and useful as a pharmaceutical agent, which is a compound represented by the formula (I) wherein ring A is an optionally substituted, nitrogen containing heterocycle, ring B is an optionally substituted monocyclic homocycle or an optionally substituted monocyclic heterocycle, Z is N or NR1 (R1 is a hydrogen atom or an optionally substituted hydrocarbon group), is a single bond or a double bond, R2 is a hydrogen atom or an optionally substituted hydrocarbon group, X is an optionally substituted spacer having 1 to 6 atoms, ring C is (1) an optionally substituted homocycle or (2) an optionally substituted heterocycle other than a ring represented by (II) (X′ is S, O, SO, or CH2), and at least one of ring B and ring C has substituent(s), provided that N-{(1S,2R)-1-(3,5-difluorobenzyl)-3-[(3-ethylbenzyl)amino]2 hydroxypropyl}5,6 dimethyl 4 oxo 1,4 dihydrothieno[2,3-d]pyrimidine-2-carboxamide is excluded, or a salt thereof.