87219-21-4

Basic information

• Product Name: L-Phenylalanine, N-[[(2-chloroethyl)amino]carbonyl]-, methyl ester
• CAS NO: 87219-21-4
• Molecular Formula: C13H17ClN2O3
• Molecular Weight: 284.743
• Mol File: 87219-21-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-[[(2-chloroethyl)amino]carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-[[(2-chloroethyl)amino]carbonyl]-, methyl ester(87219-21-4)
• EPA Substance Registry System: L-Phenylalanine, N-[[(2-chloroethyl)amino]carbonyl]-, methyl ester(87219-21-4)

Safety Data

• Hazardous Substances Data: 87219-21-4(Hazardous Substances Data)

Upstream product

• 1943-83-5 2-chloroethyl isothiocyanate 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 87219-26-9 (S)-5-benzyl-3-(2-chloroethyl)imidazolidine-2,4-dione 
• 87219-27-0 3-(2-hydroxyethyl)-5-benzylhydantoin 

Relevant articles and documents

CYCLIZATION REACTIONS OF N-(2-CHLOROETHYLCARBAMOYL) AMINO ACIDS

Intramolecular cyclization of the N-(2-chloroethylcarbamoyl) derivatives of glycine, valine and phenylalanine give imidazolidone, oxazoline and hydantoin derivatives.The imidazolidone and oxazoline derivatives possess alkylating activity toward NBP, but the hydantoins do not.N-(2-Chloroethylcarbamoyl)glycine reacts with the mercapto group of cysteine; thus, this alkylating group may be useful for receptor labelling.