872513-35-4

Basic information

• Product Name: (2,4-difluoro-phenyl)-{3-[5-(3-dimethylamino-prop-1-ynyl)-2-methoxy-phenyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}-amine
• Synonyms: (2,4-difluoro-phenyl)-{3-[5-(3-dimethylamino-prop-1-ynyl)-2-methoxy-phenyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}-amine
• CAS NO: 872513-35-4
• Molecular Weight: 434.448
• Mol File: 872513-35-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2,4-difluoro-phenyl)-{3-[5-(3-dimethylamino-prop-1-ynyl)-2-methoxy-phenyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}-amine(CAS DataBase Reference)
• NIST Chemistry Reference: (2,4-difluoro-phenyl)-{3-[5-(3-dimethylamino-prop-1-ynyl)-2-methoxy-phenyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}-amine(872513-35-4)
• EPA Substance Registry System: (2,4-difluoro-phenyl)-{3-[5-(3-dimethylamino-prop-1-ynyl)-2-methoxy-phenyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}-amine(872513-35-4)

Safety Data

• Hazardous Substances Data: 872513-35-4(Hazardous Substances Data)

Upstream product

• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 872513-28-5 3-(5-bromo-2-methoxy-phenyl)-6-chloro-1H-pyrazolo[3,4-d]pyrimidine 
• 872513-27-4 (5-bromo-2-methoxy-phenyl)-(2,4-dichloro-pyrimidin-5-yl)-methanone 
• 872513-54-7 (5-bromo-2-methoxy-phenyl)-(2,4-dichloro-pyrimidin-5-yl)-methanol 
• 872513-29-6 [3-(5-bromo-2-methoxy-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]-(2,4-difluoro-phenyl)-amine 
• 7223-38-3 N,N-Dimethylpropargylamin 

Relevant articles and documents

Pyrazoloheteroaryls: Novel p38α MAP kinase inhibiting scaffolds with oral activity

A test library with three novel p38α inhibitory scaffolds and a narrow set of substituents was prepared. Appropriate combination of substituent and scaffold generated potent p38α inhibitors, for example, pyrazolo[3,4-b]pyridine 9, pyrazolo[3,4-d]pyrimidin