872866-27-8Relevant articles and documents
APOPTOSIS-INDUCING AGENTS
-
, (2014/03/22)
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti apoptotic Bcl-xL protein.
ARYLSULFONAMIDE COMPOUNDS
-
Page/Page column 31; 33-34, (2008/12/05)
The invention relates generally to small molecules that mimic the biological activity of certain peptides and proteins, to compositions containing them and to their use. In particular, the invention relates to compounds of the general formula (I) that mim
N-acylsulfonamide apoptosis promoters
-
, (2008/06/13)
N-Benzoyl arylsulfonamides having the formula are BCL-Xl inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-Xl inhibiting compositions and methods of promoting apoptosis in a mammal.