875414-12-3

Basic information

• Product Name: [2-chloro-4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl]-(5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)-methanone
• CAS NO: 875414-12-3
• Molecular Weight: 469.853
• Mol File: 875414-12-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [2-chloro-4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl]-(5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: [2-chloro-4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl]-(5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)-methanone(875414-12-3)
• EPA Substance Registry System: [2-chloro-4-(5-trifluoromethyl-pyrazol-1-yl)-phenyl]-(5,11-dihydro-benzo[b]pyrido[2,3-e][1,4]diazepin-6-yl)-methanone(875414-12-3)

Safety Data

• Hazardous Substances Data: 875414-12-3(Hazardous Substances Data)

Upstream product

• 16287-36-8 6,11-dihydro-5H-pyrido{2,3-b][1,5]benzodiazepine 
• 95-54-5 1,2-diamino-benzene 
• 21900-54-9 2-chloro-4-fluorobenzoyl chloride 
• 2252-51-9 2-choro-4-fluorobenzoic acid 
• 2942-59-8 2-chloronicotinic acid 
• 220603-04-3 (2-chloro-4-fluorophenyl)-(6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-6-yl)-methanone 
• 20154-03-4 3-(trifluoromethyl)pyrazole 

Relevant articles and documents

Pyridobenzodiazepines: A novel class of orally active, vasopressin V 2 receptor selective agonists

Our efforts in seeking low molecular weight agonists of the antidiuretic peptide hormone arginine vasopressin (AVP) have led to the identification of the clinical candidate WAY-151932 (VNA-932). Further exploration of the structural requirements for agonist activity has provided another class of potent, orally active, non-peptidic vasopressin V2 receptor selective agonists exemplified by the 5,11-dihydro-pyrido[2,3-b][1,5]benzodiazepine as a candidate for further development.