875755-36-5

Basic information

• Product Name: 7-chloro-1,2,3,4-tetrahydronaphthalen-1-aMine
• Synonyms: 7-chloro-1,2,3,4-tetrahydronaphthalen-1-aMine
• CAS NO: 875755-36-5
• Molecular Formula: C10H12ClN
• Molecular Weight: 181.66198
• Mol File: 875755-36-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-chloro-1,2,3,4-tetrahydronaphthalen-1-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-chloro-1,2,3,4-tetrahydronaphthalen-1-aMine(875755-36-5)
• EPA Substance Registry System: 7-chloro-1,2,3,4-tetrahydronaphthalen-1-aMine(875755-36-5)

Safety Data

• Hazardous Substances Data: 875755-36-5(Hazardous Substances Data)

Upstream product

• 42071-42-1 7-chloro-3,4-dihydronaphthalen-1(2H)-one oxime 
• 26673-32-5 7-chloro-3,4-dihydro-2H-naphthalen-1-one 

Relevant articles and documents

Synthesis method of levo-amino compound

The invention discloses a synthesis method of a levo-amino compound S-7-chloro-1,2,3,4-tetrahydronaphthalene-1-amine. The method includes the steps of: performing a reaction to a raw material, 7-chloro-1-tetralone, with hydroxylamine to generate oxime; performing hydrogenation reduction to the oxime to prepare racemized amine; performing a one-pot dynamic kinetic resolution reaction to the product amine with lipase, a racemization catalyst and an acyl group donor; and hydrolyzing a resolution reaction product to prepare the S-7-chloro-1,2,3,4-tetrahydronaphthalene-1-amine. The method has simple operations, high product yield, high optical purity of the resolution product, and the like.