87676-07-1

Basic information

• Product Name: N-(1-methoxypropan-2-yl)-2,4-dimethylthiophen-3-amine
• Synonyms: 3-Thiophenamine, N-(2-methoxy-1-methylethyl)-2,4-dimethyl-; 87676-07-1
• CAS NO: 87676-07-1
• Molecular Formula: C₁₀H₁₇NOS
• Molecular Weight: 199.3131
• Mol File: 87676-07-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 301.8°C at 760 mmHg
• Flash Point: 136.3°C
• Density: 1.064g/cm³
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: N-(1-methoxypropan-2-yl)-2,4-dimethylthiophen-3-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-methoxypropan-2-yl)-2,4-dimethylthiophen-3-amine(87676-07-1)
• EPA Substance Registry System: N-(1-methoxypropan-2-yl)-2,4-dimethylthiophen-3-amine(87676-07-1)

Safety Data

• Hazardous Substances Data: 87676-07-1(Hazardous Substances Data)

Upstream product

• 106582-33-6 N-(1-methoxyprop-2-yl)-2,4-dimethyltetrahydrothien-3-ylidenimine 
• 7783-06-4 hydrogen sulfide 
• 87685-15-2 2,4-dimethyl-3-amino-thiophene 
• 5878-19-3 Methoxyacetone 
• 37143-54-7 methoxyisopropylamine 
• 77-78-1 dimethyl sulfate 

Relevant articles and documents

Preparation method of refined dimethenamid

The present invention relates to the field of herbicides, and discloses a preparation method of refined dimethenamid. The method comprises the steps of 1) in the presence of an acid, carrying out a first contact reaction on a compound having a structure represented by a formula (1) shown in the description and (2S)-1-hydroxypropyl-2-amine to obtain a compound having a structure represented by a formula (2) shown in the description; 2) in the presence of first alkali, carrying out second contact reaction on the compound with the structure as shown in the formula (2) and a methylation reagent to obtain a compound with a structure as shown in a formula (3) defined in the description; and 3) in the presence of second alkali, carrying out third contact reaction on the compound with the structure shown in the formula (3) and chloroacetyl chloride to obtain refined dimethenamid. The method disclosed by the invention is mild in reaction condition, high in yield, simple and convenient to operate and very suitable for industrial preparation.

Tunable ferrocenyl diphosphine ligands for the Ir-catalyzed enantioselective hydrogenation of N-aryl imines

Ferrocenyl diphosphines R2PF-P(R′)2 are effective, tunable ligands for the iridium catalyzed enantioselective hydrogenation of N-aryl imines in the presence of iodide and acid promoters. Structure-activity/selectivity correlations were found for the hydrogenation of N-(2-ethyl-6-methylphenyl)-N-(1′-methoxymethyl)-ethylidene-amine (MEA-imine) and for 2,3,3-trimethylindolenine (TMI). Extremely high catalytic activity and moderate to good enantioselectivity were observed for the MEA imine using a catalyst generated in situ from [Ir(cod)Cl]2 and (R)-(S)-PPF-P(3,5-Xyl)2 (xyliphos). With the same type of catalysts, several other N-aryl imines can be hydrogenated with enantioselectivities between 31 and 96%, albeit with lower catalyst activities.

Preparation of N-thienyl-chloroacetamides and tetrahydro-thien-3-ylidenimines

The invention provides compounds of formula I STR1 wherein R is C1-4 alkoxy-C2-4 alkyl of which the C1-4 alkoxy group is separated by at least 2 C-atoms from the N-atom to which R is bound, each of R2 and R4 independently is CH3 or C2 H5 and R5 is H or CH3, the preparation of such compounds and the use of such compounds for the preparation of N-(thien-3-yl)-chloroacetamides.