87685-15-2Relevant articles and documents
SULFONYLUREA DERIVATIVES AND USES THEREOF
-
Paragraph 0947-0948, (2020/12/30)
The present disclosure relates to compounds of Formula (I) and to their prodrugs, pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein are useful for inhibiting the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inflammatory, autoinflammatory and autoimmune diseases and cancers.
Thiophene derivatives of the new solid form and its preparation method and use thereof
-
Paragraph 0065; 0066; 0067; 0068; 0069, (2018/07/30)
The invention relates to thiophene derivatives of the new solid form and its preparation method and use, the thiophene derivatives of the new solid state forms is compound 1 crystalline form I, compound 1 crystalline form II, compound 2 crystalline form I, compound 2 crystalline form II, the invention also relates to containing thiophene derivatives of the new solid form pharmaceutical composition and can be used for the local anesthetic and/or analgesic drug in the field of application. The present invention provides powder X - with obvious-ray diffraction Atlas characteristics of the new solid form, its preparation method is simple, it is convenient to store, is suitable for preparing a plurality of preparations,
Herbicidal N-thienyl-chloroacetamides
-
, (2008/06/13)
The invention provides 5-membered heteroaromatic compounds of formula I wherein Ar is a 5-membered heteroaromatic group comprising 1 or 2 heteroatoms selected from O, S and N and linked by a ring C-atom to the N-atom of the N(Y)COCH2 Cl group to which it is bound, whereby where Ar is pyrazolyl, said N(Y)COCH2 Cl group is in the 4-position, and Y is as specified in the description, the use of these compounds as herbicides, compositions for facilitating such use and the preparation of the chloroacetamides.