877068-88-7Relevant articles and documents
ANTIVIRAL PHOSPHINATE COMPOUNDS
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Page/Page column 91-92, (2008/06/13)
The invention is related to anti-viral phosphinate compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
A systematic approach to the optimization of substrate-based inhibitors of the hepatitis C virus NS3 protease: Discovery of potent and specific tripeptide inhibitors
Llinàs-Brunet, Montse,Bailey, Murray D.,Ghiro, Elise,Gorys, Vida,Halmos, Ted,Poirier, Martin,Rancourt, Jean,Goudreau, Nathalie
, p. 6584 - 6594 (2007/10/03)
The inadequate efficacy and tolerability of current therapies for the infectious liver disease caused by the hepatitis C virus have warranted significant efforts in the development of new therapeutics. We have previously reported competitive peptide inhib