877238-97-6

Basic information

• Product Name: 1-Cyclohexene-1-carboxylic acid, 3-(1-ethylpropoxy)-5-(formylamino)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3R,4S,5R)-
• CAS NO: 877238-97-6
• Molecular Formula: C16H27NO7S
• Molecular Weight: 377.459
• Mol File: 877238-97-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Cyclohexene-1-carboxylic acid, 3-(1-ethylpropoxy)-5-(formylamino)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3R,4S,5R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexene-1-carboxylic acid, 3-(1-ethylpropoxy)-5-(formylamino)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3R,4S,5R)-(877238-97-6)
• EPA Substance Registry System: 1-Cyclohexene-1-carboxylic acid, 3-(1-ethylpropoxy)-5-(formylamino)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3R,4S,5R)-(877238-97-6)

Safety Data

• Hazardous Substances Data: 877238-97-6(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 332047-22-0 ethyl (3R,4S,5R)-5-N-formylamino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate 
• 312904-12-4 ethyl (3R,4S,5R)-5-amino-3-(1-ethylpropoxy)-4-hydroxy-1-cyclohexene-1-carboxylate 
• 204254-96-6 (1S,5R,6S)-5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic acid ethyl ester 

Downstream Products

• 312904-18-0 ethyl (3R,4R,5S)-4-N-acetylamino-5-N-allylamino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate 
• 312904-15-7 ethyl (3R,4R,5S)-5-N-allylamino-4-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate 
• 196618-13-0 oseltamivir 
• 312904-17-9 ethyl (3R,4S,5R)-5-amino-3-(1-ethylpropoxy)-4-methanesulfonyloxy-1-cyclohexene-1-carboxylate 

Relevant articles and documents

Process for the preparation of 4,5-diamino shikimic acid derivatives

The present invention relates to a process for the preparation of a 4,5-diamino shikimic acid derivative of formula and pharmaceutically acceptable addition salts thereof wherein R1, R1′ are independent of each other H or alkyl, R2 is an alkyl and R3, R4 are independent of each other H or an alkanoyl, with the proviso that not both R3 and R4 are H. 4,5-diamino shikimic acid derivatives of formula I, especially the (3R,4R,5S)-5-amino-4-acetylamino-3-(1-ethyl-propoxy)-cyclohex-1-ene-carboxylic acid ethyl ester and its pharmaceutically acceptable additional salts are potent inhibitors of viral neuraminidase.