87736-75-2

Basic information

• Product Name: 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone
• Synonyms: 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone;O-tert-ButyldiMethylsilyl-benzyl Alcohol 4-(2,2,2-Trifluoroethanone);4'-[(tert-Butyldimethylsilyloxy)methyl]-2,2,2-trifluoroacetophenone;4'-[(tert-Butyldimethylsilyloxy)methyl]-2,2,2-trifluoroacetophenone
• CAS NO: 87736-75-2
• Molecular Formula: C₁₅H₂₁F₃O₂Si
• Molecular Weight: 318.4067496
• Product Categories: Aromatics;Intermediates
• Mol File: 87736-75-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 145°C/0.8mmHg(lit.)
• Appearance: /
• Refractive Index: 1.4660 to 1.4700
• Storage Temp.: Refrigerator
• Solubility: Dichloromethane, Diethyl Ether, Ethyl Acetate, Methanol
• CAS DataBase Reference: 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone(87736-75-2)
• EPA Substance Registry System: 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone(87736-75-2)

Safety Data

• Hazardous Substances Data: 87736-75-2(Hazardous Substances Data)

Usage

Description

1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone is a light yellow oil with unique chemical properties. It is an intermediate compound that plays a significant role in the synthesis of trifluoromethyldiazirine, a valuable molecule for scientific research and applications.

Uses

Used in Chemical Research:
1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone is used as an intermediate in the preparation of trifluoromethyldiazirine for chemical research purposes. Trifluoromethyldiazirine is a photo-induced cross-linking probe that aids in exploring amyloid formation, a crucial area of study in understanding various diseases and developing potential treatments.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone serves as a key intermediate in the synthesis of trifluoromethyldiazirine. 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone is utilized in the development of drugs targeting amyloid-related diseases, such as Alzheimer's and Parkinson's, by enabling researchers to study the formation and structure of amyloid proteins.
Used in Material Science:
1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone is also used in material science as an intermediate for the synthesis of trifluoromethyldiazirine. 1-[4-[[[(1,1-DiMethylethyl)diMethylsilyl]oxy]Methyl]phenyl]-2,2,2-trifluoro-ethanone has potential applications in the development of advanced materials with unique properties, such as improved stability and reactivity, which can be beneficial in various industrial applications.

Upstream product

• 340-07-8 N-(trifluoroacetyl)piperidine 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 
• 383-63-1 ethyl trifluoroacetate, 
• 360-92-9 N,N-diethyl-2,2,2-trifluoroacetamide 
• 18282-51-4 4-iodo-benzyl alcohol 
• 147283-96-3 4-(tert-butyldimethylsiloxymethyl)iodobenzene 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 873-75-6 4-bromobenzenemethanol 

Downstream Products

• 87736-77-4 1-<4-<(tert-butyldimethylsilyloxy)methyl>phenyl>-2,2,2-trifluoro-1-ethanone oxime 
• 87736-83-2 3-<4-<(tert-butyldimethylsiloxy)methyl>phenyl>-3-trifluoromethyldiaziridine 
• 87736-89-8 1-<<4-<3-(trifluoromethyl)-3H-diazirin-3-yl>benzoyl>oxy>-2,5-pyrrolidinedione 
• 85559-46-2 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic acid 
• 87736-77-4 4-[(tert-butyldimethylsiloxy)methyl]-2,2,2-trifluoroacetophenone oxime 
• 1575814-87-7 2,3,5-tri-O-benzoyl-1-O-[4-(3-trifluoromethyl-3H-diazirin-3-yl)benzyl]-β-D-ribofuranose 
• 1575814-81-1 1-O-[4-(3-trifluoromethyl-3H-diazirin-3-yl)benzyl]-β-D-ribofuranose 
• 1575814-88-8 1-O-[4-(3-trifluoromethyl-3H-diazirin-3-yl)benzyl]-5-O-(4,4′-dimethoxytrityl)-β-D-ribofuranose 
• 1575814-89-9 3-O-(tert-butyldimethylsilyl)-1-O-[4-(3-trifluoromethyl-3H-diazirin-3-yl)benzyl]-5-O-(4,4′-dimethoxytrityl)-β-D-ribofuranose 
• 1575814-90-2 2-O-(tert-butyldimethylsilyl)-1-O-[4-(3-trifluoromethyl-3H-diazirin-3-yl)benzyl]-5-O-(4,4′-dimethoxytrityl)-β-D-ribofuranose 
• 1197982-80-1 (R)-2-acetamido-3-methoxy-N-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzyl)propanamide 
• 148058-40-6 2-(4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl)acetic acid 
• 400781-14-8 4-(3-(trifluoromethyl)-3H-diazirin-3-yl)benzyl methanesulfonate 
• 87736-80-9 4-[(tert-butyldimethylsiloxy)methyl]-2,2,2-trifluoroacetophenone-O-(4-toluenesulfonyl) oxime 

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