878733-86-9

Basic information

• Product Name: 1,3-dihydro-1'H-spiro[indene-2,2'-quinazolin]-4'(3'H)-one
• Synonyms: 1,3-dihydro-1'H-spiro[indene-2,2'-quinazolin]-4'(3'H)-one
• CAS NO: 878733-86-9
• Molecular Weight: 250.3
• Mol File: 878733-86-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-dihydro-1'H-spiro[indene-2,2'-quinazolin]-4'(3'H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dihydro-1'H-spiro[indene-2,2'-quinazolin]-4'(3'H)-one(878733-86-9)
• EPA Substance Registry System: 1,3-dihydro-1'H-spiro[indene-2,2'-quinazolin]-4'(3'H)-one(878733-86-9)

Safety Data

• Hazardous Substances Data: 878733-86-9(Hazardous Substances Data)

Upstream product

• 2975-41-9 2,3-dihydro-1H-inden-2-amine 
• 28144-70-9 anthranilic acid amide 
• 615-13-4 2-indanone 

Relevant articles and documents

Synthesis of Flavanone and Quinazolinone Derivatives from the Ruthenium-Catalyzed Deaminative Coupling Reaction of 2′-Hydroxyaryl Ketones and 2-Aminobenzamides with Simple Amines

The cationic Ru–H complex [(C6H6)(PCy3)(CO)RuH]+BF4– (1) with 3,4,5,6-tetrachloro-1,2-benzoquinone (L1) was found to be a highly effective catalyst for the deaminative coupling reaction of 2′-hydroxyaryl ketones with simple amines to form 3-substituted flavanone products. The analogous deaminative coupling reaction of 2-aminobenzamides with branched amines directly formed 3,3-disubstituted quinazolinone products. The catalytic method efficiently installs synthetically useful flavanone and quinazolinone core structures without employing any reactive reagents.