879148-28-4

Basic information

• Product Name: C₁₀H₁₁NO₆S
• Synonyms: C₁₀H₁₁NO₆S
• CAS NO: 879148-28-4
• Molecular Weight: 273.266
• Mol File: 879148-28-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₀H₁₁NO₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₁₁NO₆S(879148-28-4)
• EPA Substance Registry System: C₁₀H₁₁NO₆S(879148-28-4)

Safety Data

• Hazardous Substances Data: 879148-28-4(Hazardous Substances Data)

Upstream product

• 16588-16-2 ethyl 4-chloro-3-nitrobenzoate 
• 1426841-88-4 C₁₀H₁₁NO₄S 

Downstream Products

• 1426841-99-7 C₂₀H₂₅N₃O₆S 
• 1426842-08-1 C₂₁H₂₃N₃O₆S 
• 1426841-89-5 C₁₂H₁₄N₂O₇S 
• 1426841-90-8 C₁₃H₁₆N₂O₇S 
• 1426841-91-9 C₁₄H₁₈N₂O₇S 
• 1426841-92-0 C₁₃H₁₆N₂O₇S 
• 1426841-93-1 C₁₆H₂₀N₂O₇S 
• 1426841-94-2 C₁₀H₁₀N₂O₇S 
• 1426841-95-3 C₁₁H₁₂N₂O₇S 
• 1426841-96-4 C₁₂H₁₄N₂O₇S 
• 1426841-97-5 C₁₁H₁₂N₂O₇S 
• 1426841-98-6 C₁₄H₁₆N₂O₇S 
• 1426842-09-2 C₁₆H₂₃N₃O₆S 
• 1426842-10-5 C₂₀H₂₂N₄O₆S 

Relevant articles and documents

Synthesis and evaluation of methylsulfonylnitrobenzamides (MSNBAs) as inhibitors of the thyroid hormone receptor-coactivator interaction

We previously identified the methylsulfonylnitrobenzoates (MSNBs) that block the interaction of the thyroid hormone receptor with its obligate transcriptional coactivators and prevent thyroid hormone signaling. As part of our lead optimization work we demonstrated that sulfonylnitrophenylthiazoles (SNPTs), which replace the ester linkage of MSNBs with a thiazole, also inhibited coactivator binding to TR. Here we report that replacement of the ester with an amide (methylsulfonylnitrobenzamides, MSNBA) also provides active TR antagonists.