88048-78-6

Basic information

• Product Name: 2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester
• Synonyms: 2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester;methyl 2-(bromomethyl)thiophene-3-carboxylate
• CAS NO: 88048-78-6
• Molecular Formula: C₇H₇BrO₂S
• Molecular Weight: 235.09828
• Mol File: 88048-78-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester(88048-78-6)
• EPA Substance Registry System: 2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester(88048-78-6)

Safety Data

• Hazardous Substances Data: 88048-78-6(Hazardous Substances Data)

Usage

General Description

2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester is a chemical compound with the molecular formula C9H9BrO2S. It is a methyl ester of 2-(bromomethyl)-3-thiophenecarboxylic acid, which is a derivative of thiophene and contains a bromomethyl functional group. 2-(bromomethyl)-3-Thiophenecarboxylic acid methyl ester is commonly used in organic synthesis and pharmaceutical research as a building block for the production of various drugs and other organic compounds. It has potential applications in the fields of medicinal chemistry, agrochemicals, and materials science due to its structural versatility and reactivity. However, it should be handled with care due to its potential hazards and should be used in a controlled laboratory setting by trained professionals.

Upstream product

• 1918-78-1 2-methylthiophene-3-carboxylic acid 
• 53562-51-9 2-methylthiophene-3-carboxylic acid methyl ester 

Downstream Products

• 148564-47-0 milfasartan 
• 148564-34-5 methyl 2-<<4-butyl-2-methyl-6-oxo-5-<<2'-<1-(triphenylmethyl)-1H-tetrazol-5-yl><1,1'-biphenyl>-4-yl>methyl>-1(6H)-pyrimidinyl>methyl>-3-thiophenecarboxylate 
• 172292-52-3 2-[4-Butyl-5-(2'-cyano-biphenyl-4-ylmethyl)-2-methyl-6-oxo-6H-pyrimidin-1-ylmethyl]-thiophene-3-carboxylic acid methyl ester 

Relevant articles and documents

Aromatic heterocyclic lactam compound as well as preparation method and application thereof

The invention discloses an aromatic heterocyclic lactam compound as well as a preparation method and an application thereof. The invention particularly discloses an aromatic heterocyclic lactam compound shown as a formula (I), or pharmaceutically acceptable salt thereof, or an enantiomer, a diastereoisomer, a tautomer, a solvate, a polymorphic substance or a prodrug thereof, a preparation method of the aromatic heterocyclic lactam compound and an application of the aromatic heterocyclic lactam compound to pharmacy.

INTEGRASE INHIBITORS 3

The present invention provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Compounds of formula (I) are also provided.

The synthesis of four isomeric bisthienothiepinones

The displacement reaction between sodium thiophene-3-thiolate and methyl 3-(bromomethyl)thiophene-2-carboxylate (5) gave the expected thioether 7a. Basic hydrolysis afforded the carboxylic acid 7b; conversion to the acid chloride, and treatment of the latter with stannic chloride then produced the bisthienothiepinone 1. Using analogous reactions the isomers 2-4 were also synthesized.