881016-89-3

Basic information

• Product Name: A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID
• Synonyms: A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID;2-BroMo-2-(1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid;2-bromo-2-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid;1-Boc-4-(bromo-carboxy-methyl)-piperidine
• CAS NO: 881016-89-3
• Molecular Formula: C12H20BrNO4
• Molecular Weight: 322.2
• Mol File: 881016-89-3.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID(881016-89-3)
• EPA Substance Registry System: A-BROMO-1-[(1,1-DIMETHYLETHOXY)CARBONYL]-4-PIPERIDINEACETIC ACID(881016-89-3)

Safety Data

• Hazardous Substances Data: 881016-89-3(Hazardous Substances Data)

Upstream product

• 881016-88-2 4-(bromo-methoxycarbonyl-methyl)-piperidine-1-carboxylic acid tert-butyl ester 
• 168986-49-0 4-piperidine acetic acid methyl ester 
• 175213-46-4 1-t-Butoxycarbonyl-4-(methoxycarbonylmethyl)piperidine 
• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists

A series of substituted dipiperidine compounds have been synthesized and identified as selective CCR2 antagonists. Combining the most favorable substituents led to the discovery of remarkably potent CCR2 antagonists displaying IC50 values in th

Substituted dipiperidine CCR2 antagonists

Substituted dipiperidine compounds of Formula (I) or a salt, isomer, prodrug, metabolite or polymorph thereof, which are CCR2 antagonists and are useful in preventing, treating or ameliorating CCR2 mediated inflammatory syndromes, disorders or diseases in a subject in need thereof.