883230-94-2

Basic information

• Product Name: 5-BROMO-2-PYRAZOL-1-YL-PYRIMIDINE
• Synonyms: 5-BROMO-2-PYRAZOL-1-YL-PYRIMIDINE;5-Bromo-2-(1H-pyrazol-1-yl)pyrimidine
• CAS NO: 883230-94-2
• Molecular Formula: C7H5BrN4
• Molecular Weight: 225.0454
• Product Categories: Heterocycle-Pyrimidine series
• Mol File: 883230-94-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 402.2 °C at 760 mmHg
• Flash Point: 197 °C
• Appearance: /
• Density: 1.79g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-BROMO-2-PYRAZOL-1-YL-PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-PYRAZOL-1-YL-PYRIMIDINE(883230-94-2)
• EPA Substance Registry System: 5-BROMO-2-PYRAZOL-1-YL-PYRIMIDINE(883230-94-2)

Safety Data

• Hazardous Substances Data: 883230-94-2(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-pyrazol-1-yl-pyrimidine is a chemical compound with the molecular formula C7H5BrN4. It is a heterocyclic compound consisting of a pyrazole ring and a pyrimidine ring, with a bromine atom attached to the pyrazole ring. 5-Bromo-2-pyrazol-1-yl-pyrimidine has potential applications in the field of medicinal chemistry, particularly in the development of pharmaceutical drugs. It may be used as a building block in the synthesis of various biologically active molecules, and has been studied for its potential as an anticancer and antiviral agent. Additionally, 5-Bromo-2-pyrazol-1-yl-pyrimidine has been investigated for its role in the development of new materials and chemical processes. Overall, this compound has the potential to contribute to various areas of scientific research and development.

Upstream product

• 288-13-1 NH-pyrazole 
• 478258-70-7 5-bromo-2-(1H-pyrrol-1-yl)pyrimidine 
• 883230-68-0 5-bromo-2-(1H-imidazol-1-yl)pyrimidine 
• 883230-69-1 1-(5-bromopyrimidin-2-yl)-1H-benzo[d]imidazole 
• 32779-36-5 5-Bromo-2-chloropyrimidine 

Relevant articles and documents

Pyrimidine-pyrazole metal ruthenium complex with catalysis property and preparation method of complex

The invention discloses a pyrimidine-pyrazole metal ruthenium complex with a catalysis property and a preparation method of the complex and relates to synthesis and an application of a transition metal complex. A molecular formula of the pyrimidine-pyrazo

Metal-free site-selective C-N bond-forming reaction of polyhalogenated pyridines and pyrimidines

This paper presents a metal-free method for highly site-selective C-N bond-forming reaction of polyhalogenated pyridines and pyrimidines. The preferred coupling site can be tuned from the fluorine group bearing the N-heterocyclic ring to the chlorine group when changing from the pyridine ring to the pyrimidine ring. A wide array of halogenated pyridines preferentially reacted with amines at the fluorine group of the pyridine ring to generate monosubstituted halogenated pyridines with high selectivities. Different halogen atoms at various positions were produced by the pyridine ring that performed well under mild conditions. Halogenated pyrimidines underwent highly selective coupling at the chloride group with a wide range of amines having broad substrate applicability and moderate to good yields. The selectivity of the polyfluoropyridines in the developed reaction system was also tested, and the result indicated that the reaction occurred site-selectively at the ortho-position of the nitrogen ring. This reaction accommodated a wide range of halogenated groups. Thus, a wide range of chloro-, bromo-, iodo-, and fluoropyridines were generated, which have a wide utility for organic synthesis.

OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS

The present invention relates to certain substituted phenyl oxazolidinones and to processes for the synthesis of the same. This invention also relates to pharmaceutical compositions containing the compounds of the present invention as antimicrobials. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria, for example, multiple-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms, for example, Bacterioides spp. and Clostridia spp. species, and acid fast organisms, for example, Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.