885268-42-8 Usage
General Description
Tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate is a chemical compound with the molecular formula C13H24N2O2. It is a spiro compound containing a seven-membered ring fused to a five-membered ring, with a tert-butyl group and a carboxylate group attached to the nitrogen and carbon atoms, respectively. tert-butyl 2,7-diazaspiro[4.5]decane-2-carboxylate is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also shown potential as a building block in organic synthesis and as a ligand in coordination chemistry. Its unique structure and diverse reactivity make it a valuable and versatile compound in various chemical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 885268-42-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,6 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 885268-42:
(8*8)+(7*8)+(6*5)+(5*2)+(4*6)+(3*8)+(2*4)+(1*2)=218
218 % 10 = 8
So 885268-42-8 is a valid CAS Registry Number.
885268-42-8Relevant articles and documents
Synthesis and differential functionalisation of pyrrolidine and piperidine based spirodiamine scaffolds
Weinberg, Kamil,Stoit, Axel,Kruse, Chris G.,Haddow, Mairi F.,Gallagher, Timothy
, p. 4694 - 4707 (2013/07/04)
The synthesis and differential substitution/protection of a series of spirodiamine scaffolds are described. Methods for selective access to the two mono-N-methyl isomers based on 2,7-diazaspiro[4.5]decane are also described. Key precursors associated with this chemistry are prone to rearrangement and methods for circumventing this issue are reported. While direct mono-carbamoylation (Boc) was not efficient, selective deprotection of doubly Boc-protected derivatives derived from symmetrical diamines provided mono-Boc variants. N-Arylation, exemplified by a series of monosubstituted spirodiamines incorporating the 2-chloro-5-pyridyl moiety, which is a privileged nicotinic agonist substructure, has also been carried out to provide monoarylated secondary and tertiary spirodiamines variants.
