886510-09-4 Usage
General Description
3-Fluoro-2-trifluoromethyl-isonicotinic acid is a chemical compound with the molecular formula C7H3F4NO2. It is a derivative of isonicotinic acid and is characterized by the presence of a fluorine and trifluoromethyl group on the aromatic ring. 3-FLUORO-2-TRIFLUOROMETHYL-ISONICOTINIC ACID is primarily used as a building block for the synthesis of pharmaceuticals, agrochemicals, and materials. It may also exhibit biological activity and has potential applications in the development of new drugs. Overall, 3-fluoro-2-trifluoromethyl-isonicotinic acid is a valuable chemical intermediate with diverse uses in the field of organic chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 886510-09-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,5,1 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 886510-09:
(8*8)+(7*8)+(6*6)+(5*5)+(4*1)+(3*0)+(2*0)+(1*9)=194
194 % 10 = 4
So 886510-09-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H3F4NO2/c8-4-3(6(13)14)1-2-12-5(4)7(9,10)11/h1-2H,(H,13,14)
886510-09-4Relevant articles and documents
Preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and derivatives thereof
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, (2020/04/17)
The invention discloses a preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and derivatives thereof, and is characterized in that provided is the preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and the derivatives thereof by a method of introducing trifluoromethyl into 2-site of a polysubstituted pyridine ring through a free radical mechanism, wherein the preparation method is suitable for large-scale application. The method for directly carrying out trifluoromethylation reaction on the 2-site of 3-fluoro-4-pyridine carboxylic acid alkyl ester is reported forthe first time, and is simple and convenient in process, easily available in raw materials, high in conversion rate and simple in reaction post-treatment operation. Meanwhile, the selectivity of the method in introducing trifluoromethyl into the 2-site of pyridine is quite high, and a single product with trifluoromethyl substituted at the 2-site can be obtained only through simple recrystallization.
