889865-43-4

Basic information

• Product Name: 5-Bromo-2-chloropyridine N-oxide
• Synonyms: 5-Bromo-2-chloropyridine N-oxide;5-Bromo-2-chloropyridine 1-oxide, 97%
• CAS NO: 889865-43-4
• Molecular Formula: C5H3BrClNO
• Molecular Weight: 208.44042
• Product Categories: C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyridines
• Mol File: 889865-43-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 115-119 °C
• Appearance: /
• CAS DataBase Reference: 5-Bromo-2-chloropyridine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-chloropyridine N-oxide(889865-43-4)
• EPA Substance Registry System: 5-Bromo-2-chloropyridine N-oxide(889865-43-4)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 889865-43-4(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-chloropyridine N-oxide, also known as BCNO, is a chemical compound used in organic synthesis and pharmaceutical research. It is a white to off-white solid with a molecular formula of C5H3BrClNO and a molecular weight of 188.44 g/mol. BCNO is primarily used as a reagent in the preparation and modification of organic compounds, particularly pyridine derivatives. It is known for its ability to introduce functional groups into various chemical structures, making it a versatile tool in chemical and drug development. Additionally, BCNO is also employed in the study of chemical reactions and mechanisms in organic synthesis, making it a valuable reagent in the field of chemistry.

Upstream product

• 53939-30-3 5-bromo-2-chloropyridine 

Downstream Products

• 1053659-39-4 3-bromo-6-chloropyridine-2-carbonitrile 

Relevant articles and documents

Homogenous suspension of immunopotentiating compounds and uses thereof

The present invention generally relates to homogeneous suspensions of small molecule immune potentiators (SMIPs) that are capable of stimulating or modulating an immune response in a subject in need thereof. The homogeneous suspensions may be used in combinations with various antigens or adjuvants for vaccine therapies.

COMPOUNDS AND COMPOSITIONS AS TLR ACTIVITY MODULATORS

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N; X4 is N Or CR3; X5 is -CR4=CR5.

SUBSTITUTED PYRIDONE DERIVATIVE

Compounds of the formula: (I) [wherein A is the formula: (III-1) R3 is a hydrogen atom, lower alkyl, etc.; m is 0 or 1; R1 is a hydrogen atom, halogen atom, etc.; R2 is a hydroxyl, etc.; p is 0 to 4; X is a carbon atom or