89029-62-9Relevant articles and documents
1,1-Di-iodoalkenes from Aldehydes and Triphenylphosphine-Carbon Tetraiodide
Gavina, Francisco,Luis, Santiago V.,Ferrer, Patrick,Costero, Ana M.,Marco, J. Alberto
, p. 296 - 297 (1985)
The Wittig-like transformation of aliphatic and aromatic aldehydes into 1,1-di-iodoalkenes can be achieved with triphenylphosphine-carbon tetraiodide.
One-pot synthesis of 1-iodoalkynes and trisubstituted alkenes from benzylic and allylic bromides
Pelletier, Guillaume,Lie, Sharon,Mousseau, James J.,Charette, Andre B.
supporting information, p. 5464 - 5467,4 (2020/10/15)
1-Iodoalkynes are formed in moderate to high yields from readily accessible benzylic and allylic alkyl bromides by a one-pot homologation/double elimination procedure with iodoform (CHI3). The developed conditions include facile purification and avoid the use of an excess of triphenylphosphine (PPh3), as described in classical Corey-Fuchs iodoalkynylation conditions. Replacing CHI3 with CHI2Cl allows the isolation of the corresponding gem-(Z)-chloro-(E)-iodoalkene in good yield and stereoselectivity. Moreover, the use of benzhydryl bromides as nucleophiles enables the synthesis of trisubstituted alkenes under similar reaction conditions.
Highly efficient two-step synthesis of C-sp3-centered geminal diiodides
Cloarec, Jean-Manuel,Charette, Andre B.
, p. 4731 - 4734 (2007/10/03)
(Chemical Equation Presented) Trisubstituted gem-diiodoalkenes of functionalized chains are efficiently reduced to the corresponding terminal geminal diiodides in high yields upon treatment with the diazene precursor, diethyl 4-(hydrazinosulfonyl)-benzyl phosphonate.
