891260-94-9Relevant articles and documents
Histone deacetylase inhibitors with a primary amide zinc binding group display antitumor activity in xenograft model
Attenni, Barbara,Ontoria, Jesus M.,Cruz, Jonathan C.,Rowley, Michael,Schultz-Fademrecht, Carsten,Steinkuehler, Christian,Jones, Philip
scheme or table, p. 3081 - 3084 (2010/02/28)
Histone deacetylase (HDAC) inhibition causes hyperacetylation of histones leading to differentiation, growth arrest and apoptosis of malignant cells, representing a new strategy in cancer therapy. Many of the known HDAC inhibitors (HDACi) that are in clin