891782-61-9 Usage
General Description
3-PIPERAZIN-2-YL-PROPIONIC ACID, also known as PZP, is a chemical compound with the molecular formula C8H16N2O2. It is a piperazine derivative and a structural analog of the neurotransmitter GABA. PZP has been studied for its potential pharmacological properties, including as an antipsychotic and anxiolytic agent. It has also been investigated for its potential use in the treatment of conditions such as schizophrenia and bipolar disorder. Additionally, PZP has been found to have antioxidant and neuroprotective effects, making it of interest for research in the field of neurology and neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 891782-61-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,1,7,8 and 2 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 891782-61:
(8*8)+(7*9)+(6*1)+(5*7)+(4*8)+(3*2)+(2*6)+(1*1)=219
219 % 10 = 9
So 891782-61-9 is a valid CAS Registry Number.
891782-61-9Relevant articles and documents
Dual antagonists of platelet activating factor and histamine. Part 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines
Piwinski, John J.,Wong, Jesse K.,Green, Michael J.,Kaminski, James J.,Colizzo, Frank,Albanese, Margaret M.,Ganguly, Ashit K.,Billah, M. Motasim,Anthes, John C.,West Jr., Robert E.
, p. 3469 - 3474 (1998)
A series of N-acyl-4-(5,6-dihydro-11-H-benzo[5,6]cyclohepta[1,2- b]pyridin-11-ylidene)piperazines is described that are dual antagonists of PAF and histamine. The structural requirements for activity in this series parallel those of their previously reported piperidinylidene counterparts. Whereas their global minimum energy conformations are different for both series of compounds, computer assisted molecular modeling suggests that a common bioactive conformation is possible.
