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891785-18-5

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891785-18-5 Usage

General Description

3-(Benzyloxy)-5-bromo-2-chloropyridine is a chemical compound with the molecular formula C12H9BrClNO. It is a pyridine derivative with a bromo and chloro substituents on the 5th and 2nd position, respectively, and a benzyl ether group at the 3rd position. 3-(Benzyloxy)-5-broMo-2-chloropyridine is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has a wide range of applications in organic synthesis and is known for its high selectivity and reactivity in various chemical reactions. 3-(Benzyloxy)-5-bromo-2-chloropyridine is an important building block in the synthesis of various biologically active compounds and is widely used in medicinal and agricultural research.

Check Digit Verification of cas no

The CAS Registry Mumber 891785-18-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,1,7,8 and 5 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 891785-18:
(8*8)+(7*9)+(6*1)+(5*7)+(4*8)+(3*5)+(2*1)+(1*8)=225
225 % 10 = 5
So 891785-18-5 is a valid CAS Registry Number.
InChI:InChI=1S/C12H9BrClNO/c13-10-6-11(12(14)15-7-10)16-8-9-4-2-1-3-5-9/h1-7H,8H2

891785-18-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-bromo-2-chloro-3-phenylmethoxypyridine

1.2 Other means of identification

Product number -
Other names QC-8880

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:891785-18-5 SDS

891785-18-5Downstream Products

891785-18-5Relevant articles and documents

NITROGEN-CONTAINING HETEROARYL COMPOUND AND PHARMACEUTICAL USE THEREOF

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Paragraph 0568-0570, (2019/06/07)

The invention provides a compound having a GLUT9 inhibitory activity. The compound is of Formula [I] wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.

INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS

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Page/Page column 37, (2011/10/03)

The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. Th

Isoquinoline-pyridine-based protein kinase B/Akt antagonists: SAR and in vivo antitumor activity

Zhu, Gui-Dong,Gong, Jianchun,Claiborne, Akiyo,Woods, Keith W.,Gandhi, Viraj B.,Thomas, Sheela,Luo, Yan,Liu, Xuesong,Shi, Yan,Guan, Ran,Magnone, Shayna R.,Klinghofer, Vered,Johnson, Eric F.,Bouska, Jennifer,Shoemaker, Alexander,Oleksijew, Anatol,Stoll, Vincent S.,Jong, Ron De,Oltersdorf, Tilman,Li, Qun,Rosenberg, Saul H.,Giranda, Vincent L.

, p. 3150 - 3155 (2007/10/03)

The structure-activity relationships of a series of isoquinoline-pyridine-based protein kinase B/Akt antagonists have been investigated in an effort to improve the major short-comings of the lead compound 3, including poor pharmacokinetic profiles in several species (e.g., mouse iv t1/2 = 0.3 h, po F = 0%). Chlorination at C-1 position of the isoquinoline improved its pharmacokinetic property in mice (iv t1/2 = 5.0 h, po F = 51%) but resulted in >500-fold drop in potency. In a mouse MiaPaCa-2 xenograft model, an amino analog 10y significantly slowed the tumor growth, however was accompanied by toxicity.

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