89892-38-6

Basic information

• Product Name: 3-Bromo-4-cyanobenzyl bromide
• Synonyms: 3-Bromo-4-cyanobenzyl bromide;2-BroMo-4-(broMoMethyl)benzonitrile
• CAS NO: 89892-38-6
• Molecular Formula: C₈H₅Br₂N
• Molecular Weight: 274.94
• Mol File: 89892-38-6.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 356.6±37.0 °C(Predicted)
• Appearance: /
• Density: 1.92±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 3-Bromo-4-cyanobenzyl bromide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-4-cyanobenzyl bromide(89892-38-6)
• EPA Substance Registry System: 3-Bromo-4-cyanobenzyl bromide(89892-38-6)

Safety Data

• Hazardous Substances Data: 89892-38-6(Hazardous Substances Data)

Usage

General Description

3-Bromo-4-cyanobenzyl bromide is a chemical compound with the molecular formula C8H5Br2N. It is a brominated derivative of 4-cyanobenzyl bromide and is commonly used in organic synthesis and pharmaceutical research. 3-Bromo-4-cyanobenzyl bromide is a versatile building block in the preparation of various bioactive molecules and pharmaceutical intermediates. It is an important reagent for the synthesis of benzimidazole derivatives, which are known for their diverse pharmacological activities. Additionally, 3-Bromo-4-cyanobenzyl bromide has applications in the development of new drugs and agrochemicals due to its ability to selectively modify biologically active molecules. Overall, this compound plays a crucial role in the field of drug discovery and development.

Upstream product

• 53456-09-0 4-methyl-2-bromobenzoyl chloride 
• 131002-03-4 4-methyl-2- bromobenzamide 
• 7697-27-0 2-bromo-4-methylbenzoic acid 
• 42872-73-1 4-methyl-2-bromobenzonitrile 

Downstream Products

• 90110-97-7 2-bromo-4-(hydroxymethyl)benzonitrile 
• 1034188-51-6 ethyl 1-[(3-bromo-4-cyanophenyl)methyl]-1H-pyrazole-3-carboxylate 
• 1177558-39-2 4-(aminomethyl)-2-bromobenzonitrile 
• 1423134-40-0 tert-butyl 4-{3-[(3R)-3-{[(1S)-1-{5-[(3-bromo-4-cyanobenzyl)oxy]pyridin-3-yl}-3-methoxy-3-oxopropyl]carbamoyl}piperidin-1-yl]-3-oxopropyl}piperidine-1-carboxylate 
• 1177559-17-9 4-(aminomethyl)-2-bromobenzonitrile hydrochloride 
• 1177558-38-1 2-bromo-4-((1,3-dioxoisoindolin-2-yl)methyl)benzonitrile 

Relevant articles and documents

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

NEW SUBSTITUTED BIPHENYL ANALOGUES AS DUAL INHIBITORS OF AROMATASE AND SULFATASE

Provided are new biphenyl derivatives of formula (Ia). These compounds act as aromatase and sulfatase inhibitors. They are particularly useful for treating pathological conditions or diseases in which aromatase and sulfatase are involved. Moreover, provided are processes for the preparation of these compounds and pharmaceutical compositions containing said products and their use for the preparation of a medicament, in particular for the treatment of diseases characterized by aromatase and sulfatase activity such as hormone-dependent cancers.

Dual Pharmacophores - PDE4-Muscarinic Antagonistics

The present invention is directed to novel compounds of Formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions and their use as dual chromaphores having inhibitory activity against PDE4 and muscarinic acetylcholine receptors (mAChRs), and thus being useful for treating respiratory diseases.