900187-22-6

Basic information

• Product Name: (1-S)-{4-[(5-tert-butoxycarbonylamino-1-hydroxymethyl-pentyl)-isobutyl-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester
• Synonyms: (1-S)-{4-[(5-tert-butoxycarbonylamino-1-hydroxymethyl-pentyl)-isobutyl-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester
• CAS NO: 900187-22-6
• Molecular Weight: 543.725
• Mol File: 900187-22-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-S)-{4-[(5-tert-butoxycarbonylamino-1-hydroxymethyl-pentyl)-isobutyl-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1-S)-{4-[(5-tert-butoxycarbonylamino-1-hydroxymethyl-pentyl)-isobutyl-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester(900187-22-6)
• EPA Substance Registry System: (1-S)-{4-[(5-tert-butoxycarbonylamino-1-hydroxymethyl-pentyl)-isobutyl-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester(900187-22-6)

Safety Data

• Hazardous Substances Data: 900187-22-6(Hazardous Substances Data)

Upstream product

• 449806-97-7 Nα-isobutyl-Nα-(4-acetamidobenzenesulfonyl)-L-α-amino-ε-caprolactam 
• 359782-00-6 (3S)-3-isobutylamino-azepan-2-one 
• 21568-87-6 2-aminocaprolactam 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 

Downstream Products

• 874339-77-2 (1S)-(4-{[5-tert-butoxycarbonylamino-1-(diethoxyphosphoryloxy-methyl)-pentyl]-isobutyl-sulfamoyl}-phenyl)-carbamic acid tert-butyl ester 
• 874339-83-0 (2S)-nicotinic acid 6-tert-butoxycarbonylamino-2-[(4-tert-butoxycarbonylamino-benzenesulfonyl)-isobutyl-amino]-hexyl ester 
• 874339-81-8 (2S)-acetic acid 6-tert-butoxycarbonylamino-2-[(4-tert-butoxycarbonylamino-benzenesulfonyl)-isobutyl-amino]-hexyl ester 

Relevant articles and documents

Lysine sulfonamides as novel HIV-protease inhibitors: Nε-Acyl aromatic α-amino acids

A series of lysine sulfonamide analogues bearing Nε-acyl aromatic amino acids were synthesized using an efficient synthetic route. Evaluation of these novel protease inhibitors revealed compounds with high potency against wild-type and multiple-protease inhibitor-resistant HIV viruses.