90133-93-0Relevant articles and documents
New Aggregation-Induced Emitters: Tetraphenyldistyrylbenzenes
Freudenberg, Jan,Rominger, Frank,Bunz, Uwe H. F.
, p. 16749 - 16753 (2015)
The synthesis of five novel distyrylbenzene (DSB) derivatives, featuring a central tetraphenylbenzene core, is reported. The targets show aggregation-induced emission (AIE), which, however, is substituent-dependent. For the pure hydrocarbon and derivative
In vitro imaging of β-cells using fluorescent cubic bicontinuous liquid crystalline nanoparticles
Miceli,Meli,Blanchard-Desce,Bsaibess,Pampalone,Conaldi,Caltagirone,Obiols-Rabasa,Schmidt,Talmon,Casu,Murgia
, p. 62119 - 62127 (2016/07/13)
To evaluate the potential of monoolein-based cubic bicontinuous liquid crystalline nanoparticles (cubosomes) as diagnostic tools in diabetes and pancreatic β-cell transplantation, fluorescent cubosomes were formulated, entrapping within the lipid bilayer a newly synthesized, potent, hydrophobic dye. Cryo-TEM, SAXS, and DLS were performed to assess the morphological and structural aspects of this formulation. Rat pancreatic β-cells (INS-1E) readily took up the cubosome nanoparticles, as revealed by in vitro internalization tests, and flow-cytometric analyses confirmed the persistence of the fluorescence for up to 24 hours. The cytotoxicity of cubosomes at various concentrations, evaluated with a real-time analysis of proliferation, revealed that the proliferation curves relative to the less concentrated formulation (5 μM in terms of monoolein content) were comparable to the untreated cultures. INS-1E cell cycle and apoptosis supported such results. In conclusion, this formulation, with dye content in the nanomolar range, seems to be useful for β-cell imaging.
Nonlinear optical and energy-level modulation of organic alkynes by click chemistry
Miao, Zongcheng,Han, Huihui,Wang, Dong,Gao, Hong,Gu, Jianming,Hu, Huiying
, p. 4039 - 4046 (2016/07/06)
A series of novel donor–acceptor chromophores have been successfully synthesized in excellent yield by metal-free [2+2] click chemistry, which was effective in the energy-level modulation of organic the π-conjugation aniline derivatives. Meanwhile, struct