90142-14-6

Basic information

• Product Name: Acetamide, 2-[(2,2-dimethoxyethyl)amino]-N-(2-phenylethyl)-
• CAS NO: 90142-14-6
• Molecular Formula: C14H22N2O3
• Molecular Weight: 266.34
• Mol File: 90142-14-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-[(2,2-dimethoxyethyl)amino]-N-(2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-[(2,2-dimethoxyethyl)amino]-N-(2-phenylethyl)-(90142-14-6)
• EPA Substance Registry System: Acetamide, 2-[(2,2-dimethoxyethyl)amino]-N-(2-phenylethyl)-(90142-14-6)

Safety Data

• Hazardous Substances Data: 90142-14-6(Hazardous Substances Data)

Upstream product

• 1380603-46-2 2-[(2,2-dimethoxyethyl)benzylamino]-N-phenethylacetamide 
• 13156-95-1 2-chloro-N-phenethylacetamide 
• 64-04-0 phenethylamine 
• 97-97-2 chloroacetaldehyde dimethyl acetal 
• 2184-96-5 glycinyl chloride hydrochloride 
• 22483-09-6 2,2-dimethoxyethylamine 

Downstream Products

• 90142-13-5 N-(2,2-dimethoxyethyl)-N-(2-oxo-2-(2-phenethylamino)-ethyl)cyclohexanecarboxamide 
• 61196-37-0 2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-one 
• 55268-74-1 2-cyclohexanecarbonyl-1,2,3,6,7,11b-hexahydro-pyrazino[2,1-a]isoquinolin-4-one 
• 94494-35-6 4-(cyclohexylcarbonyl)-3,4-dihydro-1-(2-phenylethyl)-2(1H)-pyrazinone 

Relevant articles and documents

Preparation method for praziquantel

The invention discloses a preparation method for praziquantel. The method has a reaction route as described in the specification, wherein R1 is selected from the group consisting of C1-C4 alkanes. According to the invention, the purpose of synthesis of high-purity praziquantel from cheap and easily-available raw materials and with simple operation, mild reaction conditions, low toxicity, low hazard and low cost is realized; industrial production requirements are met; and significant application values are obtained.

PROCESS FOR THE PREPARATION OF PRAZIQUANTEL

The present disclosure describes a novel, cost-effective process for preparation of a 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino-[2,1-a]isoquinoline derivatives. Specifically, it discloses a process for the preparation of the anthelmintic drug praziquantel through the use of a novel intermediate, 2-[(2,2-dimethoxyethyl)benzyl amino]-N-phenethylacetamide. This present disclosure also describes a novel crystalline form of 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline.