90236-61-6

Basic information

• Product Name: (N^α-t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine p-nitrobenzyl ester
• Synonyms: (N^α-t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine p-nitrobenzyl ester
• CAS NO: 90236-61-6
• Molecular Weight: 600.562
• Mol File: 90236-61-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (N^α-t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine p-nitrobenzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (N^α-t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine p-nitrobenzyl ester(90236-61-6)
• EPA Substance Registry System: (N^α-t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine p-nitrobenzyl ester(90236-61-6)

Safety Data

• Hazardous Substances Data: 90236-61-6(Hazardous Substances Data)

Upstream product

• 538-37-4 dibenzyl phosphochloridate 
• 16938-11-7 N^α-t-butoxycarbonyl-L-serine p-nitrobenzyl ester 
• 67746-43-4 dibenzyl N,N-diethylphosphoramidite 
• 100-51-6 benzyl alcohol 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 3262-72-4 (S)-N-(tert-butoxycarbonyl)serine 
• 41662-50-4 dibenzyl chlorophosphite 

Downstream Products

• 90013-47-1 Nα-(t-butoxycarbonyl)-O-(benzyl)glutamyl-O-(dibenzylphosphono)serylleucine benzyl ester 
• 90013-46-0 Boc-Ser(PO₃Bzl₂)-Leu-OBzl 
• 90013-48-2 (S)-2-[(S)-2-Amino-3-(bis-benzyloxy-phosphoryloxy)-propionylamino]-4-methyl-pentanoic acid benzyl ester 
• 90013-45-9 N^α-(t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine 

Relevant articles and documents

31P NMR SPECTROSCOPY STUDIES ON THE DIORGANYL PHOSPHOROCHLORIDATE/PYRIDINE PHOSPHORYLATION PROCEDURE

The interaction of diphenyl phosphorochloridate and three dialkyl phosphorohloridates (alkyl = Et, Me, Bzl) with pyridine was shown by 31P NMR spectroscopy to lead to the formation of diorganyl phosphoropyridinium ihetrmediate.In the case of diethyl, dime

Synthesis of Casein-Related Peptides and Phosphopeptides. V The Efficient Global 'Phosphite-Triester' Phosphorylation of Protected Serine Derivatives and Peptides by Using Dibenzyl or Di-t-butyl N,N-Diethylphosphoramidite.

Both dibenzyl N,N-diethylphosphoramidite and di-t-butyl N,N-diethylphosphoramidite are shown to be suitable reagents for the efficient 1H-tetrazole-catalysed 'phosphite-triester' phosphorylation of the protected serine derivative Boc-Ser-OCH2C6H4NO2-p. Bo

Preparation of Nα-(t-Butoxycarbonyl)-O-(dibenzylphosphono)-L-serine

The protected phosphoserine synthon Nα-(t-butoxycarbonyl)-O-(dibenzylphosphono)-L-serine was prepared in three steps.Stability studies on the phosphorylating agent dibenzyl phosphorochloridate were performed by 31P n.m.r. spectroscopy.