90486-63-8

Basic information

• Product Name: 4',5-dihydroxy-2',5'-dimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone
• Synonyms: 4',5-dihydroxy-2',5'-dimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone
• CAS NO: 90486-63-8
• Molecular Weight: 396.397
• Mol File: 90486-63-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4',5-dihydroxy-2',5'-dimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone(CAS DataBase Reference)
• NIST Chemistry Reference: 4',5-dihydroxy-2',5'-dimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone(90486-63-8)
• EPA Substance Registry System: 4',5-dihydroxy-2',5'-dimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone(90486-63-8)

Safety Data

• Hazardous Substances Data: 90486-63-8(Hazardous Substances Data)

Upstream product

• 78-79-5 isoprene 
• 90509-72-1 2'-acetoxy-4,6'-bis(benzyloxy)-2,5-dimethoxy-2,2-dimethyldihydropyrano<5,6-c>chalcone 
• 90486-60-5 4,6'-bis(benzyloxy)-2'-hydroxy-2,5-dimethoxy-2,2-dimethyldihydropyrano<5,6-c>chalcone 
• 24128-11-8 6-Acetyl-5,7-dihydroxy-3,4-dihydro-2,2-dimethyl-2H-<1>benzopyran 
• 29938-08-7 2-benzyloxy-1,4-dimethyoxybenzene 
• 18113-18-3 2,5-dimethoxyphenol 
• 90509-72-1 Acetic acid 7-benzyloxy-6-[(E)-3-(4-benzyloxy-2,5-dimethoxy-phenyl)-acryloyl]-2,2-dimethyl-chroman-5-yl ester 
• 124360-67-4 3,4-dihydro-4-hydroxy-7-<2,5-dimethoxy-4-(tosyloxy)phenyl>-2,2-dimethyl-5-tosyloxy-2H,6H-benzo<1,2-b:5,4-b'>dipyran-6-one 
• 124360-66-3 2,3-dihydro-7-<2,5-dimethoxy-4-(tosyloxy)phenyl>-2,2-dimethyl-5-tosyloxy-4H,6H-benzo<1,2-b:5,4-b'>dipyran-4,6-dione 
• 124360-82-3 3-(4-benzoyloxy-2,5-dimethoxyphenyl)-9,10-dihydro-10-hydroxy-8,8-dimethyl-5-tosyloxy-4H,8H-benzo<1,2-b:3,4-b'>dipyran-4-one 
• 124360-81-2 3-(4-benzoyloxy-2,5-dimethoxyphenyl)-8,9-dihydro-8,8-dimethyl-5-tosyloxy-4H,10H-benzo<1,2-b:3,4-b'>dipyran-4,10-dione 
• 124360-62-9 7-(4-benzyloxy-2,5-dimethoxyphenyl)-2,3-dihydro-5-methoxy-2,2-dimethyl-4H,6H-benzo<1,2-b:5,4-b'>dipyran-4,6-dione 
• 124360-77-6 3-(4-benzyloxy-2,5-dimethoxyphenyl)-8,9-dihydro-5-methoxy-8,8-dimethyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-4,10-dione 
• 124360-80-1 3-(4-benzoyloxy-2,5-dimethoxyphenyl)-8,9-dihydro-5-hydroxy-8,8-dimethyl-4H,10H-benzo<1,2-b:3,4-b'>dipyran-4,10-dione 

Downstream Products

• 3044-53-9 2',4',5,5'-tetramethoxy-2,2-dimethylpyrano<6,5-h>isoflavone 
• 3044-60-8 5-hydroxy-2',4',5'-trimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone 
• 117155-38-1 4',5-diacetoxy-2',5'-dimethoxy-2,2-dimethylpyrano<6,5-h>isoflavone 

Relevant articles and documents

Synthesis of Pyranoisoflavones from Pyronochalcones: Synthesis of Elongatin and Its Angular Isomer

Elongatin (4',5-dihydroxy-2',5'-dimethoxy-2'',2''-dimethylpyranoisoflavone) was synthesized by an oxidative rearrangement of the corresponding pyronochalcone with thallium(III) nitrate and a regioselective reduction of 7-(4-benzoyloxy-2,5-dimethoxyphenyl)-2,3-dihydro-2,2-dimethyl-5-tosyloxy-4H,6H-benzodipyran-4,6-dione with sodium borohydride-palladium chloride, followed by dehydration of the resultant alcohol and hydrolysis.Its angular isomer (4',5-dihydroxy-2',5'-dimethoxy-2'',2''-dimethylpyranoisoflavone) was also synthesized from the corresponding pyronochalcone in a similar manner.

A CONVENIENT SYNTHESIS OF A LINEAR PYRANOISOFLAVONE: SYNTHESIS OF ELONGATIN AND ITS ANGULAR ISOMER

Linear 4',5-dihydroxy-2',5'-dimethoxy-2",2"-dimethyl-dihydropyranoisoflavone, which had been prepared from 6-acetyl-5-benzyloxy-7-hydroxy-2,2-dimethylchroman via four steps, was dehydrogenated with DDQ to give elongatin.Its angular isomer was als