912804-59-2

Basic information

• Product Name: C₁₂H₁₇N₃O
• CAS NO: 912804-59-2
• Molecular Weight: 219.286
• Mol File: 912804-59-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₂H₁₇N₃O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₂H₁₇N₃O(912804-59-2)
• EPA Substance Registry System: C₁₂H₁₇N₃O(912804-59-2)

Safety Data

• Hazardous Substances Data: 912804-59-2(Hazardous Substances Data)

Upstream product

• 54239-37-1 cimaterol 

Relevant articles and documents

Chiral separations of some β-adrenergic agonists and antagonists on AmyCoat column by HPLC

Sixteen β-adrenergic antagonists namely acebutalol, alprenolol, atenolol, bisoprolol, bopindolol, bufurolol, carazolol, celiprolol, indenolol, metaprolol, nebivolol, oxprenolol, practolol, propranolol, tertalol, and timolol, and two β-adrenergic agonists namely cimeterol and clenbuterol were resolved on AmyCoat (150 x 46 mm, 3 μm size of silica particle) by using (85:15:0.1, v/v/v), (90:10:0.1, v/v/v), and (95:05:0.1, v/v/v) combinations of η-heptane, ethanol, and diethylamine solvents, respectively. The flow rates used were 0.5, 1.0, 2.0, and 3.0 ml/min with detection at 225 nm. The values of capacity, separation, and resolution factors ranged from 0.38 to 19.70, 1.08-2.33, and 1.0 and 4.50, respectively. The maximum and minimum resolutions were achieved for celiprolol and bufurolol, respectively. The chiral recognition mechanisms were also discussed. The values of validation parameters were calculated.