915306-61-5

Basic information

• Product Name: (-)-(1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-en-3-ylmethanol
• Synonyms: (-)-(1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-en-3-ylmethanol
• CAS NO: 915306-61-5
• Molecular Weight: 229.322
• Mol File: 915306-61-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-(1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-en-3-ylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-en-3-ylmethanol(915306-61-5)
• EPA Substance Registry System: (-)-(1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-en-3-ylmethanol(915306-61-5)

Safety Data

• Hazardous Substances Data: 915306-61-5(Hazardous Substances Data)

Upstream product

• 1333161-38-8 (-)-(1S,2S,5R)-8-phenylmenthyl (1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate 
• 542-92-7 cyclopenta-1,3-diene 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 161661-47-8 (-)-(1R,2S,5R)-8-phenylmenthyl (1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylate 

Downstream Products

• 1333161-48-0 (-)-(1S,3S,4R)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-en-3-ylmethyl 3,5-dinitrobenzoate 
• 1033103-97-7 (+)-(1S,3S,4S,5S,6R)-3-(hydroxymethyl)-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]heptane-5,6-diol 
• 915306-63-7 (-)-(1S,3S,4R)-3-[(tert-butyldiphenylsiloxy)methyl]-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene 
• 915306-64-8 3-benzyloxymethyl-2-(1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-5-ene 
• 915306-68-2 (-)-(1S,3S,4S,5S,6R)-3-[(tert-butyldiphenylsiloxy)methyl]-2-[(1R)-1-phenylethyl]-2-azabicyclo[2.2.1]heptane-5,6-diol 
• 915306-73-9 (+)-(2S,3S,5S)-2-[(tert-butyldiphenylsiloxy)methyl]-3,5-bis(hydroxymethyl)-1-[(1R)-1-phenylethyl]pyrrolidine 
• 915306-69-3 3-benzyloxymethyl-2-(1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]heptane-5,6-diol 
• 915306-70-6 acetic acid 5,6-dihydroxy-2-(1-phenyl-ethyl)-2-aza-bicyclo[2.2.1]hept-3-ylmethyl ester 

Relevant articles and documents

Endo-benzonorbornen-2-ol as an efficient non-natural chiral auxiliary in the asymmetric aza-Diels-Alder reactions between cyclopentadiene and (1-phenylethyl)iminoacetates

Exo-2-azabicyclo[2.2.1]hept-5-enes were obtained by cycloaddition reactions between cyclopentadiene and protonated (S)- and (R)-1-phenylethylimines of (1R,endo)-benzonorbornen-2-yl glyoxylate. The non-natural (1R,endo)-benzonorbornen-2-ol proved to be an

Stereoselective synthesis of polyhydroxylated pyrrolidines: a route to novel 3,5-bis(hydroxymethyl)pyrrolidines from 2-azabicyclo[2.2.1]hept-5-enes

An efficient preparation of racemic and chiral 2-functionalized-3,5-bis(hydroxymethyl)pyrrolidines is described. The method uses 2-azabicyclo[2.2.1]hept-5-enes, readily obtained from glyoxylates of aliphatic amines and cyclopentadiene, as starting material. The hydroxylation of the double bond followed by the oxidative cleavage of the six-membered ring and in situ reduction of the dialdehyde intermediate gives the title pyrrolidines.