918523-44-1

Basic information

• Product Name: {3-[(Benzyloxy)carbonyl]-2,4-difluorophenyl}amine
• Synonyms: {3-[(Benzyloxy)carbonyl]-2,4-difluorophenyl}amine;BENZYL 3-AMINO-2,6-DIFLUOROBENZOATE
• CAS NO: 918523-44-1
• Molecular Formula: C₁₄H₁₁F₂NO₂
• Molecular Weight: 263.2394464
• Mol File: 918523-44-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: {3-[(Benzyloxy)carbonyl]-2,4-difluorophenyl}amine(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[(Benzyloxy)carbonyl]-2,4-difluorophenyl}amine(918523-44-1)
• EPA Substance Registry System: {3-[(Benzyloxy)carbonyl]-2,4-difluorophenyl}amine(918523-44-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 918523-44-1(Hazardous Substances Data)

Usage

Description

3-[(Benzyloxy)carbonyl]-2,4-difluorophenylamine is a complex organic chemical compound characterized by the presence of a benzyloxycarbonyl group, a difluorophenyl group, and an amine functional group. 3-[(Benzyloxy)carbonyl]-2,4-difluorophenylamine is known for its potential applications in organic synthesis and medicinal chemistry due to its unique structural features and possible biological activities.

Uses

Used in Organic Synthesis:
3-[(Benzyloxy)carbonyl]-2,4-difluorophenylamine is used as a building block or intermediate in the synthesis of more complex organic molecules. Its structural diversity and reactivity make it a valuable component in creating novel compounds with specific properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3-[(Benzyloxy)carbonyl]-2,4-difluorophenylamine is used as a precursor or a key component in the development of new pharmaceuticals. Its potential biological activities and interactions with biological targets make it a promising candidate for drug discovery and design.
Further Research:
Given the complex nature of 3-[(Benzyloxy)carbonyl]-2,4-difluorophenylamine, further research is necessary to fully understand its properties, reactivity, and potential applications in various industries. This may include exploring its use in materials science, environmental applications, or other areas where its unique structure and properties could be advantageous.

Upstream product

• 367-25-9 2,4-difluorophenylamine 
• 501-53-1 benzyl chloroformate 
• 13528-93-3 1,2-bis-(chlorodimethylsilyl)ethane 

Downstream Products

• 1254565-63-3 propane-1-sulfonic acid {3-[5-(6-chloro-pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluoro-phenyl}-amide 
• 1103234-56-5 2,6-difluoro-3-(propane-1-sulfonylamino)benzoic acid 
• 1186194-32-0 2,6-difluoro-3-(propylsulfonamido)benzoyl chloride 
• 918504-27-5 N-[3-(5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluoro-phenyl]propane-1-sulfonamide 
• 918523-45-2 2,6-difluoro-3-(propane-1-sulfonylamino)-benzoic acid benzyl ester 

Relevant articles and documents

PYRROLO [2, 3. B] PYRIDINES WHICH INHIBIT RAF PROTEIN KINASE

Compounds (I) and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof are described. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof, and forms thereof are active on each of BRaf and c-Raf -1 protein kinase, and may also be active on either or both of A-Raf and B-Raf V600E protein kinase. Also described are methods of use thereof to treat diseases and conditions, including melanoma, colorectal cancer, thyroid cancer, ovarian cancer, and biliary tract cancer.

PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS

Compounds of formula III which are active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.