920025-43-0Relevant articles and documents
Use of NK-1 receptor antagonists in pruritus
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Page/Page column 7, (2014/12/12)
The invention relates to methods for treating pruritus with an NK-1 receptor antagonist. The invention further relates to pharmaceutical compositions comprising NK-1 receptor antagonist.
Process for making hydroisoindoline tachykinin receptor antagonists
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Page/Page column 11; 12, (2008/06/13)
The present invention is directed to a process for preparing certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The compounds are useful in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.