923571-15-7 Usage
Description
2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one is a chemical compound that serves as an impurity in the synthesis of Donezepil (D531750), a nootropic drug. It is characterized by its unique molecular structure, featuring a 1H-inden-1-one core with a 2-isonicotinoyl group and two methoxy substituents at the 5,6 positions. 2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one also acts as an inhibitor of acetylcholinesterase, an enzyme involved in the breakdown of acetylcholine, a neurotransmitter essential for cognitive function.
Uses
Used in Pharmaceutical Industry:
2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one is used as an impurity in the synthesis of Donezepil (D531750), a nootropic agent. Its presence in the synthesis process is crucial for the development of this cognitive-enhancing drug, which aims to improve memory, learning, and overall cognitive performance.
Used in Neurochemistry Research:
As an inhibitor of acetylcholinesterase, 2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one plays a significant role in neurochemistry research. It can be utilized to study the effects of acetylcholinesterase inhibition on cognitive function and neurotransmission, providing valuable insights into the development of potential therapeutic agents for neurological disorders associated with cognitive decline.
Used in Drug Development:
2-isonicotinoyl-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one's ability to inhibit acetylcholinesterase makes it a potential candidate for drug development in the treatment of various cognitive disorders. Researchers can explore its potential as a lead compound or use it as a template to design new molecules with improved efficacy and selectivity in inhibiting acetylcholinesterase, ultimately leading to the development of novel therapeutic agents for cognitive enhancement and neuroprotection.
Check Digit Verification of cas no
The CAS Registry Mumber 923571-15-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,3,5,7 and 1 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 923571-15:
(8*9)+(7*2)+(6*3)+(5*5)+(4*7)+(3*1)+(2*1)+(1*5)=167
167 % 10 = 7
So 923571-15-7 is a valid CAS Registry Number.
923571-15-7Relevant articles and documents
PROCESS FOR THE PREPARATION OF DONEPEZIL AND INTERMEDIATE COMPOUNDS THEREOF AS WELL AS HYDRATES OF DONEPEZIL
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Page/Page column 13-14, (2008/06/13)
The present invention relates to a new process for the preparation of intermediate compounds useful in the manufacture of donepezil, or a pharmaceutically-acceptable salt thereof, and also relates to processes for preparing donepezil and to the novel intermediates per se. In addition the invention relates to various hydrated forms of donepezil.
