92405-82-8

Basic information

• Product Name: Pyrazine, 2,3-bis(4-methylphenyl)-
• CAS NO: 92405-82-8
• Molecular Formula: C18H16N2
• Molecular Weight: 260.338
• Mol File: 92405-82-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Pyrazine, 2,3-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2,3-bis(4-methylphenyl)-(92405-82-8)
• EPA Substance Registry System: Pyrazine, 2,3-bis(4-methylphenyl)-(92405-82-8)

Safety Data

• Hazardous Substances Data: 92405-82-8(Hazardous Substances Data)

Upstream product

• 4858-85-9 2,3-dichloropyrazine 
• 5720-05-8 4-methylphenylboronic acid 
• 1218-89-9 4,4'-dimethylbenzoin 
• 107-15-3 ethylenediamine 
• 3457-48-5 1,2-di(4-methylphenyl)-1,2-ethanedione 
• 1489-06-1 2,3-diphenyl-5,6-dihydropyrazine 
• 92405-78-2 5,6-bis(p-methylphenyl)-2,3-dihydropyrazine 

Downstream Products

• 952677-46-2 5-phenyl-2,3-di-p-tolylpyrazine 
• 92405-96-4 5,6-bis(p-methylphenyl)-2,3-diacetoxy-2,3-dihydropyrazine 
• 92405-89-5 2,3-bis(p-methylphenyl)pyrazine 1,4-dioxide 
• 92405-88-4 2,3-bis(p-methylphenyl)pyrazine 1-oxide 

Relevant articles and documents

Silica gel an efficient catalyst for one-pot synthesis of pyrazines from ethylenediamine and 1, 2-diketones and their analogs

A straightforward one-pot synthesis of pyrazines from ethylenediamine and 1, 2-diketones/ α-hydroxy ketone/α-bromo ketone under solvent-free conditions at room temperature is described. This environmentally benign process has the edge on previous methods in respect of workup procedure, ease and cost of reaction, and use and generation of hazardous substances. The catalyst is recovered, characterized, and proved to be recyclable for successive four runs examined with appreciable conversions.

Synthesis of Chiral Piperazines via Hydrogenation of Pyrazines Activated by Alkyl Halides

A facile method has been developed for the synthesis of chiral piperazines through Ir-catalyzed hydrogenation of pyrazines activated by alkyl halides, giving a wide range of chiral piperazines including 3-substituted as well as 2,3- and 3,5-disubstituted

Catalyst-free protocol for the synthesis of quinoxalines and pyrazines in PEG

A facile and simple catalyst-free protocol has been developed for the condensation of 1,2-diketones with aromatic 1,2-diamines in polyethylene glycol (PEG), providing quinoxaline derivatives in good yields. The important features of the methodology are broad substrates scope, simple workup, catalyst free, environmentally benign, and no requirement for metal catalysts. It is noteworthy that the cyclization reaction of 1,2-diketones with aliphatic 1,2-diamines is also conducted smoothly to afford pyrazines in good yields under the standard conditions. In addition, PEG could be recovered easily and was reused without evident loss in activity