924868-84-8

Basic information

• Product Name: 4'-Nitro-[1,1'-biphenyl]-2-carboxaldehyde
• Synonyms: 4'-Nitro-[1,1'-biphenyl]-2-carboxaldehyde;2-Formyl-4'-nitrobiphenyl, 2-(4-Nitrophenyl)benzaldehyde
• CAS NO: 924868-84-8
• Molecular Formula: C₁₃H₉NO₃
• Molecular Weight: 227
• Mol File: 924868-84-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4'-Nitro-[1,1'-biphenyl]-2-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Nitro-[1,1'-biphenyl]-2-carboxaldehyde(924868-84-8)
• EPA Substance Registry System: 4'-Nitro-[1,1'-biphenyl]-2-carboxaldehyde(924868-84-8)

Safety Data

• Hazardous Substances Data: 924868-84-8(Hazardous Substances Data)

Upstream product

• 24067-17-2 4-nitrophenylboronic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 636-98-6 p-nitrobenzene iodide 
• 40138-16-7 2-formylbenzene boronic acid 
• 100-01-6 4-nitro-aniline 
• 1947-33-7 4-nitrobenzenediazonium 4-methylbenzenesulfonate 
• 1256169-22-8 bis[2-(diethoxymethyl)phenyl]zinc 
• 586-78-7 para-nitrophenyl bromide 
• 100-52-7 benzaldehyde 

Downstream Products

• 75158-95-1 C₁₉H₁₂N₂O₂ 

Relevant articles and documents

Alkylative Dearomatization by Using an Unactivated Aryl Nitro Group as a Leaving Group: Access to Diversified Alkylated Spiro[5.5]trienones

The cleavage of an unactivated aryl nitro group triggered by alkyl radicals enables a dearomative cyclization, affording diversified alkylated spiro[5.5]trienones in good yields. Using readily available compounds (toluene and analogues, alkanes, ethers, ketones, etc.) as alkylating reagents, various alkyls have been implanted into the spirocycles via C(sp3)-H and Ar-NO2 bond activation with high functional group tolerance. This protocol provides a distinct method for the activation of the aryl nitro group.

Phosphine-Free Suzuki Cross-Coupling Reaction Using an Efficient and Reusable Pd Catalyst in an Aqueous Medium under Microwave Irradiation

We report here an improved, highly efficient, and general method for the ligand-free Suzuki cross-coupling reaction to the synthesis of biaryls, bipyridyls, thienylpyridine, and allylphenols. Microwave irradiation of (het)aryl halides and (hetaryl, allyl)arylboronic acid N-methyl-iminodiacetic acid (MIDA) ester, using polyurea microencapsulated palladium catalyst (Pd EnCat 30), gave the coupling adducts 1a-x in excellent yields in just 10-18 min.

An efficient and new protocol for phosphine-free Suzuki coupling reaction using palladium-encapsulated and air-stable MIDA boronates in an aqueous medium

A simple methodology that uses a system based on polyurea microencapsulated palladium (PdEnCat 30) and aryl or (2-pyridyl) MIDA boronates for Suzuki-Miyaura cross-coupling reactions of (hetero)aryl halides in water-alcohol under phosphine-free conditions was developed. This journal is the Partner Organisations 2014.