928312-14-5

Basic information

• Product Name: 2-Propanol, 1-[(4-fluorophenyl)sulfonyl]-2-methyl-3-(phenylmethoxy)-, (2R)-
• CAS NO: 928312-14-5
• Molecular Formula: C17H19FO4S
• Molecular Weight: 338.4
• Mol File: 928312-14-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 1-[(4-fluorophenyl)sulfonyl]-2-methyl-3-(phenylmethoxy)-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 1-[(4-fluorophenyl)sulfonyl]-2-methyl-3-(phenylmethoxy)-, (2R)-(928312-14-5)
• EPA Substance Registry System: 2-Propanol, 1-[(4-fluorophenyl)sulfonyl]-2-methyl-3-(phenylmethoxy)-, (2R)-(928312-14-5)

Safety Data

• Hazardous Substances Data: 928312-14-5(Hazardous Substances Data)

Upstream product

• 116216-91-2 (S)-2-benzyloxymethyl-2-methyloxirane 
• 928312-13-4 C₁₇H₁₉FO₂S 
• 371-42-6 4-Fluorothiophenol 

Downstream Products

• 928312-15-6 C₁₀H₁₃FO₄S 
• 90357-06-5 (R)-bicalutamide 
• 890658-79-4 C₁₀H₁₁FO₅S 

Relevant articles and documents

Bacillus subtilis epoxide hydrolase-catalyzed preparation of enantiopure 2-methylpropane-1,2,3-triol monobenzyl ether and its application to expeditious synthesis of (R)-bicalutamide

Expeditious synthesis of (R)-bicalutamide (1), a synthetic antiandrogen, from enantiopure 2-methylpropane-1,2,3-triol monobenzyl ether (4) was achieved. An engineered Bacillus subtilis epoxide hydrolase worked enantioselectively on the racemic epoxide (7) to provide the above starting material in highly enantiomerically enriched state.