93406-82-7

Basic information

• Product Name: ethyl 2-amino-3,3-diphenylpropanoate
• Synonyms: ethyl 2-amino-3,3-diphenylpropanoate
• CAS NO: 93406-82-7
• Molecular Weight: 269.343
• Mol File: 93406-82-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-amino-3,3-diphenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-amino-3,3-diphenylpropanoate(93406-82-7)
• EPA Substance Registry System: ethyl 2-amino-3,3-diphenylpropanoate(93406-82-7)

Safety Data

• Hazardous Substances Data: 93406-82-7(Hazardous Substances Data)

Upstream product

• 270078-91-6 5-(diphenylmethyl)imidazolidine-2,4-dione 
• 947-91-1 Diphenylacetaldehyde 
• 64-17-5 ethanol 
• 62653-26-3 2-amino-3,3-diphenylpropionic acid 

Downstream Products

• 107202-37-9 (1-hydroxymethyl-2,2-diphenyl-ethyl)-carbamic acid tert-butyl ester 
• 92646-33-8 2-amino-3,3-diphenyl-1-propanol 

Relevant articles and documents

Bisoxazoline and bioxazoline chiral ligands bearing 4-diphenylmethyl shielding substituents. Diels-Alder reaction of cyclopentadiene with 3-acryloyl-2-oxazolidinone catalyzed by the aqua nickel(II) complex

Enantiopure 2-amino-3,3-diphenyl-1-propanol was synthesized by the hidantoin route starting from diphenyl-acetaldehyde followed by subsequent functional group transformations and optical resolution by a chiral HPLC. The amino alcohol can be converted into two new chiral ligands: 4,4'-bis(diphenylmethyl)-2,2'-bioxazoline and 2,2'-isopropylidenebis(4-diphenylmethyloxazoline), and further to complexes with copper(II) trifluoromethanesulfonate and nickel(II) perchlorate hexahydrate. The nickel(II) aqua complex obtained from the bisoxazoline effectively catalyzed the Diels-Alder reactions of cyclopentadiene with 3-acryloyl-2-oxazolidinone in high endo-selectivities and moderate enantioselectivities via a square planar transition structure.