934415-57-3

Basic information

• Product Name: trifluoro-methanesulfonic acid 4-(17-hydroxy-13-methyl-3-oxo-17-phenyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl ester
• CAS NO: 934415-57-3
• Molecular Weight: 572.645
• Mol File: 934415-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trifluoro-methanesulfonic acid 4-(17-hydroxy-13-methyl-3-oxo-17-phenyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: trifluoro-methanesulfonic acid 4-(17-hydroxy-13-methyl-3-oxo-17-phenyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl ester(934415-57-3)
• EPA Substance Registry System: trifluoro-methanesulfonic acid 4-(17-hydroxy-13-methyl-3-oxo-17-phenyl-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-11-yl)-phenyl ester(934415-57-3)

Safety Data

• Hazardous Substances Data: 934415-57-3(Hazardous Substances Data)

Upstream product

• 5571-36-8 ethylene deltenone 
• 934415-54-0 C₃₇H₄₆O₆ 
• 934415-52-8 C₂₆H₃₂O₄ 
• 72136-99-3 C₂₆H₃₂O₃ 
• 934415-56-2 17-hydroxy-11-(4-hydroxy-phenyl)-13-methyl-17-phenyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-cyclopenta[a]phenanthren-3-one 
• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 

Relevant articles and documents

Discovery of novel phosphorus-containing steroids as selective glucocorticoid receptor antagonist

Mifepristone is a non-selective antagonist of 3-oxosteroid receptors with both abortifacient and anti-diabetic activities. For glucocorticoid receptor (GR) program, we sought an unexplored, synthetically accessible phosphorus-containing steroidal mimetic of mifepristone, suitable for parallel synthesis of analogues. One compound 4a, with high oral bioavailability (59%) in rat, exhibited functional antagonism of GR in oral glucose tolerance test (OGTT). Thus this series of compounds might be potentially useful for the treatment of type II diabetes.