934586-49-9

Basic information

• Product Name: 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine
• Synonyms: 4-(2-(Piperidin-1-yl)ethoxy)phenylboronic acid, pinacol ester;4-[2-(Piperidin-1-yl)ethoxy]benzeneboronicacid,pinacolester95%
• CAS NO: 934586-49-9
• Molecular Formula: C₁₉H₃₀BNO₃
• Molecular Weight: 331.27
• Product Categories: blocks;BoronicAcids
• Mol File: 934586-49-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 448.9°C at 760 mmHg
• Flash Point: 225.3°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 2.99E-08mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: Keep Cold
• PKA: 8.63±0.10(Predicted)
• CAS DataBase Reference: 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine(934586-49-9)
• EPA Substance Registry System: 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine(934586-49-9)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 934586-49-9(Hazardous Substances Data)

Usage

General Description

1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine is a chemical compound with a complex molecular structure. It contains a piperidine ring, an ethyl chain, and a boron-containing group. The boron-containing group is specifically a 1,3,2-dioxaborolane, which consists of a boron atom and a cyclic five-membered ring. 1-(2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine may have potential applications in organic synthesis, materials science, or pharmaceutical research, and its specific properties and uses would need to be further studied and elucidated. Additionally, its complex structure and the presence of boron suggest that it may have unique reactivity or coordination properties, which could make it of interest to researchers in various fields.

InChI:InChI=1/C19H30BNO3/c1-18(2)19(3,4)24-20(23-18)16-8-10-17(11-9-16)22-15-14-21-12-6-5-7-13-21/h8-11H,5-7,12-15H2,1-4H3

Upstream product

• 46230-75-5 methanesulfonic acid 2-piperidin-1-yl-ethyl ester 
• 269409-70-3 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 
• 3040-44-6 1-piperidinoethanol 
• 2008-75-5 N-chloroethylpiperidine hydrochloride 
• 540-38-5 p-Iodophenol 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 1427186-73-9 C₂₇H₂₈FNO 

Relevant articles and documents

Discovery of 1-(4-(4-Amino-3-(4-(2-morpholinoethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea (CHMFL-FLT3-213) as a Highly Potent Type II FLT3 Kinase Inhibitor Capable of Overcoming a Variety of FLT3 Kinase Mutan

FLT3-ITD mutant has been observed in about 30% of AML patients and extensively studied as a drug discovery target. On the basis of our previous study that ibrutinib (9) exhibited selective and moderate inhibitory activity against FLT3-ITD positive AML cel