269409-70-3 Usage
Description
4-Hydroxyphenylboronic acid pinacol ester is an organic compound that is a derivative of boronic acid, featuring a phenol group with a hydroxyl group attached to the para position and a pinacol ester group. It is a yellow to light brown crystalline powder and is known for its reactivity in various chemical reactions, particularly in the field of organic synthesis.
Uses
Used in Chemical Synthesis:
4-Hydroxyphenylboronic acid pinacol ester is used as a reagent in chemical synthesis for its ability to participate in various organic reactions, including the formation of carbon-carbon bonds.
Used in Suzuki Coupling Chemistry:
In the field of organic chemistry, 4-Hydroxyphenylboronic acid pinacol ester is used as a key component in Suzuki coupling reactions, which are widely employed for the formation of biaryl compounds. These reactions are significant in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
Used in the Pharmaceutical Industry:
4-Hydroxyphenylboronic acid pinacol ester is utilized as an intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in the Synthesis of Advanced Materials:
4-Hydroxyphenylboronic acid pinacol ester is also used as a building block in the creation of advanced materials, such as organic semiconductors and optoelectronic devices, due to its ability to form stable and functional molecular structures.
Check Digit Verification of cas no
The CAS Registry Mumber 269409-70-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,6,9,4,0 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 269409-70:
(8*2)+(7*6)+(6*9)+(5*4)+(4*0)+(3*9)+(2*7)+(1*0)=173
173 % 10 = 3
So 269409-70-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H17BO3/c1-11(2)12(3,4)16-13(15-11)9-5-7-10(14)8-6-9/h5-8,14H,1-4H3
269409-70-3Relevant articles and documents
One-pot synthesis of Ag-Cu-Cu2O/C nanocomposites derived from a metal-organic framework as a photocatalyst for borylation of aryl halide
Annas, Dicky,Bae, Jong-Seong,Hira, Shamim Ahmed,Park, Kang Hyun,Park, Sungkyun,Song, Sehwan
, p. 32965 - 32972 (2021/12/07)
Mixed metal-metal oxide/C (Ag-Cu-Cu2O/C) nanocomposites were synthesized by the heat treatment of a metal-organic framework under a N2 flow using the one-pot synthesis method. The as-prepared nanocomposites were characterized using a range of techniques,
Recyclable Pd2dba3/XPhos/PEG-2000 System for Efficient Borylation of Aryl Chlorides: Practical Access to Aryl Boronates
Cai, Mingzhong,Huang, Bin,Luo, Chengkai,Xu, Caifeng
, (2021/12/02)
Pd2dba3/XPhos in poly(ethylene glycol) (PEG-2000) is shown to be a highly stable and efficient catalyst for the borylation of aryl chlorides with bis(pinacolato)diboron. The borylation reaction proceeds smoothly at 110 °C, delivering a wide variety of aryl boronates in good to excellent yields with high functional group tolerance. The crude products were easily isolated via simple extraction of the reaction mixture with cyclohexane. Moreover, both expensive Pd2dba3 and XPhos in PEG-2000 system could be readily recycled and reused more than six times without loss of catalytic efficiency.
Nickel Hydride Catalyzed Cleavage of Allyl Ethers Induced by Isomerization
Kathe, Prasad M.,Berkefeld, Andreas,Fleischer, Ivana
supporting information, p. 1629 - 1632 (2021/02/09)
This report discloses the deallylation of O - and N -allyl functional groups by using a combination of a Ni-H precatalyst and excess Bronsted acid. Key steps are the isomerization of the O - or N -allyl group through Ni-catalyzed double-bond migration followed by Bronsted acid induced O/N-C bond hydrolysis. A variety of functional groups are tolerated in this protocol, highlighting its synthetic value.