935248-47-8Relevant articles and documents
Synthesis of a ring-expanded bryostatin analogue
Trost, Barry M.,Yang, Hanbiao,Thiel, Oliver R.,Frontier, Alison J.,Brindle, Cheyenne S.
, p. 2206 - 2207 (2008/02/01)
A ring-expanded bryostatin analogue was synthesized by utilizing a Ru-catalyzed tandem tetrahydropyran formation, a Pd-catalyzed tandem dihydropyran formation, and a ring-closing metathesis (RCM) as key steps. The analogue possesses potent antitumor activ